Covering: 2013. Previous review: Nat. Prod. Rep., 2014, 31, 160–258 This review covers the
literature published in 2013 for marine natural products (MNPs), with 982 citations (644 for …

Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …

Microtubules (composed of α-and β-tubulin heterodimers) play a pivotal role in mitosis and
cell division, and are regarded as an excellent target for chemotherapeutic agents to treat …

Marine alkaloid rigidins are cytotoxic compounds known to kill cancer cells at nanomolar
concentrations by targeting the microtubule network. Here, a rigidin analogue containing a …

Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal
intriguing structures. They are not only widespread in terrestrial habitats but can also …

This review summarizes recent literature (2000–2015) on the synthesis and pharmaceutical
properties of pyrrolopyrimidines. These modified pyrimidine bases, fused to a pyrrole ring …

Photoactivated chemotherapy (PACT) is a promising cancer treatment modality that kills
cancer cells via photochemical uncaging of a cytotoxic drug. Most ruthenium‐based …

In 1985 the first lamellarins were isolated from a small oceanic sea snail. Today, more than
50 lamellarins have been inventoried and numerous derivatives synthesized and tested as …

Fused heterocycles are reported to demonstrate variety of biological activities such as
anticancer, antibacterial, antifungal and anti-inflammatory, and are thus exhaustively utilized …