The role of immune checkpoint inhibitors in cancer therapy

AM Basudan - Clinics and Practice, 2022 - mdpi.com
Over the years, immune checkpoint inhibitors (CPIs) have become a powerful treatment
strategy in the field of cancer immunotherapy. In the last decade, the number of FDA …

The Sarcoma-Specific Instrument to Longitudinally Assess Health-Related Outcomes of the Routine Care Cycle

N Mosku, P Heesen, S Christen, MF Scaglioni, B Bode… - Diagnostics, 2023 - mdpi.com
Patient-based health related quality of life (HRQoL) measurements are associated with an
improvement in quality of care and outcomes. For a complex disease such as sarcoma …

Real-world effectiveness, safety, and health-related quality of life in patients receiving adjuvant nivolumab for melanoma in Belgium and Luxembourg: Results of …

A Rogiers, L Willemot, L McDonald… - Cancers, 2023 - mdpi.com
Simple Summary PRESERV MEL (P rospective and RE trospective S tudy of nivolumab th
ER apy in adju V ant MEL anoma) is a real-world observational study evaluating the …

Randomized phase 2 trial of tremelimumab and durvalumab in combination versus sequentially in recurrent platinum‐resistant ovarian cancer

EM Hinchcliff, A Knisely, N Adjei, B Fellman, Y Yuan… - Cancer, 2024 - Wiley Online Library
Background Single‐agent immune checkpoint inhibitors (ICIs) have demonstrated limited
responses in recurrent ovarian cancer; however, 30%–40% of patients achieve stable …

[HTML][HTML] Retrospective analysis: checkpoint inhibitor accessibility for thoracic and head and neck cancers and factors influencing it in a tertiary centre in India

V Patil, G Abraham, M Ravikrishna… - …, 2022 - ncbi.nlm.nih.gov
Background Access to cancer care is an issue in low and low middle-income countries. The
problem is worse with respect to access to new therapies like checkpoint inhibitors. Hence …

PD1 ligand functionality a biomarker of response to anti PD1 treatment in patients with HNSCC

B Kaufman, T Taha, O Abramov, Y Zohar… - NPJ Precision …, 2024 - nature.com
Therapies targeting the PD-1/PD-L1 pathway have transformed head and neck squamous
cell carcinoma (HNSCC) treatment. However, predicting the response to anti-PD-1 therapy …

Immune checkpoint inhibitor-related chronic pneumonitis: a case report and literature review

YD Wang, S Yuan, C Wen, Z Ji, B Xiang, B Wang… - …, 2023 - Taylor & Francis
Immune checkpoint inhibitor (ICI)-related chronic pneumonitis is rare. Limited information is
available on the characteristics of this condition. Herein, we present the case of a 54-year …

Developing a delivery strategy for combined drug treatment with multi-targeting immunoliposomes

M Kumari, KC Chen, FY Ke, PL Pan, EPGN Putu… - Journal of Drug Delivery …, 2024 - Elsevier
With the use of targeting delivery systems, drugs can be specifically administered to tumor
cells based on the abundant expression of cell surface markers with minimal expression in …

Mechanisms of myocardial toxicity of antitumor drugs and potential therapeutic strategies: A review of the literature

Y Jia, Q Wu, Z Yang, R Sun, K Zhang, X Guo… - Current Problems in …, 2024 - Elsevier
With the successive development of chemotherapy drugs, good results have been achieved
in clinical application. However, myocardial toxicity is the biggest challenge. Anthracyclines …

Clinical Characterization of the Expression of Insulin-Like Growth Factor Binding Protein 1 and Tumor Immunosuppression Caused by Ferroptosis of Neutrophils in …

Y Wang, L Xing, L Deng, X Wang, D Xu… - … Journal of General …, 2023 - Taylor & Francis
Purpose The efficacy of immunotherapy for non-small cell lung cancer (NSCLC) is limited
owing to cold tumors and drug resistance. Therefore, it is important to identify the molecular …