Squamous cell carcinoma (SCC) is an epithelial malignancy involving many anatomical
sites and is the most common cancer capable of metastatic spread. Development of early …

Until recently, the division of pulmonary carcinomas into small cell lung cancer (SCLC) and
non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the …

The use of potent therapies inhibiting critical oncogenic pathways active in epithelial
cancers has led to multiple resistance mechanisms, including the development of highly …

Most patients with non–small cell lung cancer (NSCLC) are diagnosed with advanced
cancer. These guidelines only include information about stage IV NSCLC. Patients with …

Introduction The emergence of treatments for non-small cell lung carcinoma (NSCLC) with
differential efficacy and toxicity between subtypes has highlighted the importance of specific …

Introduction The current WHO classification of lung cancer states that a diagnosis of SCLC
can be reliably made on routine histological and cytological grounds but …

Abstract Context.—“Undifferentiated tumor” refers to a heterogeneous group of neoplasms
with little or no evidence of differentiation on routine light microscopic morphology …

The differentiation between major histological types of lung cancer, such as
adenocarcinoma (ADC), squamous cell carcinoma (SCC), and small-cell lung cancer …

Abstract Thyroid transcription factor-1 (TTF-1) is a tissue-specific transcription factor that
plays a critical role in the normal development of embryonic epithelial cells of the thyroid and …

This study was aimed to evaluate the utility of a panel of antibodies, consisting of thyroid
transcription factor-1 (TTF-1), p63, and cytokeratins (CK) 5/6 for distinguishing between …