The epithelial to mesenchymal transition (EMT) is a fundamental developmental process
essential for normal embryonic development. It is also important during various pathogenic …

Over 50 years after its discovery in early chick embryos, the concept of epithelial-
mesenchymal transition (EMT) is now widely applied to morphogenetic studies in both …

The transcription factor RUNX1 first came to prominence due to its involvement in the t (8;
21) translocation in acute myeloid leukemia (AML). Since this discovery, RUNX1 has been …

Aims In primary central nervous system tumours, epithelial‐to‐mesenchymal transition
(EMT) gene expression is associated with increased malignancy. However, it has also been …

Aim To investigate the roles of cell migration and invasion mediated by Twist in
endometriosis. Methods The protein levels and locations of Twist, N‐cadherin and E …

Epithelial‐mesenchymal transition (EMT) or its reverse process mesenchymal‐epithelial
transition (MET) occurs in multiple physiological and pathological processes. However …

Polycythemia vera (PV) is a stem cell disorder characterized by hyperproliferation of the
myeloid lineages and the presence of an activating JAK2 mutation. To elucidate …

Background In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from
hemogenic endothelium in the floor of the dorsal aorta and subsequently migrate to …

Induced pluripotent stem cells (iPSCs) are generated by reprogramming adult cells back into
an embryonic-like state. iPSCs can be differentiated into various cell types, making them a …

As our understanding of Epithelial Mesenchymal Transition (EMT) increases, the original
binary concept of E versus M no longer fits with experimental evidence. Re-definition of the …