Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-
malignant diseases. This is consistent with numerous findings about differentiation …

Glyphosate in the concentrations corresponding to environmental or occupational exposure
has been shown to induce epigenetic changes potentially involved in carcinogenesis. This …

Background Despite a clear link between aging and cancer, there has been inconclusive
evidence on how biological age (BA) may be associated with cancer incidence. Methods We …

Observational data have shown that some cancer survivors develop chronic conditions like
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …

Abstract α-Klotho (klotho) is a protein involved in suppressing oxidative stress and
inflammation. In animal models, it is reported to underlie numerous aging phenotypes and …

Background DNA methylation (DNAm) is an epigenetic regulator of gene expression
programs that can be altered by environmental exposures, aging, and in pathogenesis …

Biological age (BA) is important for clinical monitoring and preventing aging-related
disorders and disabilities. Clinical and/or cellular biomarkers are measured and integrated …

Background: Particulate matter (PM) is a complex mixture. Geographic variations in PM may
explain the lack of consistent associations with breast cancer. Objective: We aimed to …

Epigenetic clocks use DNA methylation to estimate biological age. Whether body
composition and physical activity are associated with these clocks is not well understood …

Simple Summary Many modalities used to treat or control cancer lead to accelerated aging
in cancer survivors. However, the effects of cancer treatments on aging in individuals with …