Lineage tracing meets single-cell omics: opportunities and challenges
A fundamental goal of developmental and stem cell biology is to map the developmental
history (ontogeny) of differentiated cell types. Recent advances in high-throughput single …
history (ontogeny) of differentiated cell types. Recent advances in high-throughput single …
A community-based transcriptomics classification and nomenclature of neocortical cell types
To understand the function of cortical circuits, it is necessary to catalog their cellular
diversity. Past attempts to do so using anatomical, physiological or molecular features of …
diversity. Past attempts to do so using anatomical, physiological or molecular features of …
[HTML][HTML] Molecular topography of an entire nervous system
We have produced gene expression profiles of all 302 neurons of the C. elegans nervous
system that match the single-cell resolution of its anatomy and wiring diagram. Our results …
system that match the single-cell resolution of its anatomy and wiring diagram. Our results …
Construction of a cross-species cell landscape at single-cell level
Individual cells are basic units of life. Despite extensive efforts to characterize the cellular
heterogeneity of different organisms, cross-species comparisons of landscape dynamics …
heterogeneity of different organisms, cross-species comparisons of landscape dynamics …
A stony coral cell atlas illuminates the molecular and cellular basis of coral symbiosis, calcification, and immunity
S Levy, A Elek, X Grau-Bové, S Menéndez-Bravo… - Cell, 2021 - cell.com
Stony corals are colonial cnidarians that sustain the most biodiverse marine ecosystems on
Earth: coral reefs. Despite their ecological importance, little is known about the cell types …
Earth: coral reefs. Despite their ecological importance, little is known about the cell types …
Single-cell resolution of lineage trajectories in the Arabidopsis stomatal lineage and developing leaf
Dynamic cell identities underlie flexible developmental programs. The stomatal lineage in
the Arabidopsis leaf epidermis features asynchronous and indeterminate divisions that can …
the Arabidopsis leaf epidermis features asynchronous and indeterminate divisions that can …
Mapping single-cell atlases throughout Metazoa unravels cell type evolution
Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the
origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison …
origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison …
[HTML][HTML] Single-cell transcriptomics identifies conserved regulators of neuroglandular lineages
J Steger, AG Cole, A Denner, T Lebedeva… - Cell Reports, 2022 - cell.com
Communication in bilaterian nervous systems is mediated by electrical and secreted signals;
however, the evolutionary origin and relation of neurons to other secretory cell types has not …
however, the evolutionary origin and relation of neurons to other secretory cell types has not …
Planted Graphene Quantum Dots for Targeted, Enhanced Tumor Imaging and Long‐Term Visualization of Local Pharmacokinetics
While photoluminescent graphene quantum dots (GQDs) have long been considered very
suitable for bioimaging owing to their protein‐like size, superhigh photostability and in vivo …
suitable for bioimaging owing to their protein‐like size, superhigh photostability and in vivo …
Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse development
Waddington's epigenetic landscape is a metaphor frequently used to illustrate cell
differentiation. Recent advances in single-cell genomics are altering our understanding of …
differentiation. Recent advances in single-cell genomics are altering our understanding of …