Objective End‐stage renal disease (ESRD) is a major consequence of lupus nephritis, but
how this risk has changed over time is unknown. We conducted this systematic review to …

Objective To determine trends in survival among adult and paediatric patients with systemic
lupus erythematosus (SLE) from 1950 to the present. Methods We performed a systematic …

Mechanistic target of rapamycin (mTOR, also known as mammalian target of rapamycin) is a
ubiquitous serine/threonine kinase that regulates cell growth, proliferation and survival …

OBJECTIVES: This review examines the burden and patterns of disease in systemic lupus
erythematosus (SLE) and the influence and interactions of gender, ethnicity, age, and …

Objective The Georgia Lupus Registry is a population‐based registry designed to improve
our ability to estimate the incidence and prevalence of systemic lupus erythematosus (SLE) …

Oxidative stress is increased in systemic lupus erythematosus (SLE), and it contributes to
immune system dysregulation, abnormal activation and processing of cell-death signals …

Clinical and laboratory manifestations and outcome of systemic lupus erythematosus (SLE)
may vary in different populations. A prospective multinational inception cohort should prove …

The mechanistic target of rapamycin (mTOR) is a ubiquitous serine/threonine kinase, which
plays pivotal roles in integrating growth signals on a cellular level. To support proliferation …

Several recent studies have suggested that the incidence of systemic lupus erythematosus
(SLE) is increasing. The female to male ratio varies from 4· 3 to 13· 6. SLE is more common …

Antimalarials have shown beneficial effects on systemic lupus erythematosus (SLE) activity.
Our aim was to investigate whether antimalarials protect against thrombosis and influence …