Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Versatile polyphenolic platforms in regulating cell biology

H Cao, L Yang, R Tian, H Wu, Z Gu, Y Li - Chemical Society Reviews, 2022 - pubs.rsc.org
Polyphenolic materials are a class of fascinating and versatile bioinspired materials for
biointerfacial engineering. In particular, due to the presence of active chemical groups, a …

Manipulation of stem cells fates: the master and multifaceted roles of biophysical cues of biomaterials

X Wan, Z Liu, L Li - Advanced Functional Materials, 2021 - Wiley Online Library
Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …

3D cell culture: recent development in materials with tunable stiffness

D Baruffaldi, G Palmara, C Pirri… - ACS applied bio …, 2021 - ACS Publications
It is widely accepted that three-dimensional cell culture systems simulate physiological
conditions better than traditional 2D systems. Although extracellular matrix components …

[HTML][HTML] Stimuli-responsive materials: A smart way to study dynamic cell responses

M Bril, S Fredrich, NA Kurniawan - Smart Materials in Medicine, 2022 - Elsevier
Cells in the body reside within the extracellular matrix (ECM), a three-dimensional
environment that not only provides structural support for the cells, but also influences cellular …

A hierarchical‐structured mineralized nanofiber scaffold with osteoimmunomodulatory and osteoinductive functions for enhanced alveolar bone regeneration

Y He, M Tian, X Li, J Hou, S Chen… - Advanced …, 2022 - Wiley Online Library
Alveolar bone resorption is a major cause of teeth loss and jeopardizes the osseointegration
of dental implants, greatly affecting patient's quality of life and health. It is still a great …

Scaffold geometry modulation of mechanotransduction and its influence on epigenetics

P Han, GA Gomez, GN Duda, S Ivanovski, PSP Poh - Acta biomaterialia, 2023 - Elsevier
The dynamics of cell mechanics and epigenetic signatures direct cell behaviour and fate,
thus influencing regenerative outcomes. In recent years, the utilisation of 2D geometric (ie …

Regulation of dormancy during tumor dissemination: the role of the ECM

A Mukherjee, JJ Bravo-Cordero - Cancer and Metastasis Reviews, 2023 - Springer
The study of the metastatic cascade has revealed the complexity of the process and the
multiple cellular states that disseminated cancer cells must go through. The tumor …

Coordinated Biophysical Stimulation of MSCs via Electromagnetized Au‐Nanofiber Matrix Regulates Cytoskeletal‐to‐Nuclear Mechanoresponses and Lineage …

RK Singh, AG Kurian, V Sagar, I Park… - Advanced Functional …, 2023 - Wiley Online Library
Biophysical stimulation regulates stem cell functions, including proliferation and
differentiation. Matrix nanotopography and external forces, such as electromagnetic fields …

Three-dimensional heart extracellular matrix enhances chemically induced direct cardiac reprogramming

Y Jin, H Kim, S Min, YS Choi, SJ Seo, E Jeong… - Science …, 2022 - science.org
Direct cardiac reprogramming has emerged as a promising therapeutic approach for cardiac
regeneration. Full chemical reprogramming with small molecules to generate …