At present, the incidence of cancer is becoming more and more common, but its treatment
has always been a problem. Although a small number of cancers can be treated, the …

Simple Summary Dysregulated microRNA (miRNA) expression has been described in the
initiation and progression of a wide spectrum of hematologic malignancies. Moreover …

Abstract Background Indoleamine 2, 3-dioxygenase 1 (IDO1) catalyzes the first and rate-
limiting step in converting tryptophan to kynurenine. Chimeric antigen receptor (CAR) T cells …

Abstract Background Indoleamine 2, 3-dioxygenase 1 (IDO1) is a critical regulator of T cell
function, contributing to immune tolerance. Upregulation of IDO1 has been found in many …

Hyperserotonemia is the most replicated biochemical anomaly associated with autism
spectrum disorder (ASD) and has been reported in 35–46% of individuals with ASD …

Immunotherapy, designed to exploit the functions of the host immune system against tumors,
has shown considerable potential against several malignancies. However, the utility of …

Colorectal cancer (CRC) is regarded as one of the commonest cancer types around the
world. Due to the poor understanding on the causes of CRC formation and progression, this …

Prognostic, diagnostic or predictive biomarkers are urgently needed for assessment of
chronic graft-versus-host disease (cGvHD), a major risk for patients undergoing allogeneic …

Introduction Acute graft versus host disease (aGVHD) is a potentially lethal complication
after allogeneic stem cell transplantation. Biomarkers are used to estimate the risk of aGVHD …

Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a functional therapy for a
plethora of hematologic malignancies and immune disorders. Graft‐versus‐host disease …