The biochemistry and molecular biology of lipid accumulation in oleaginous microorganisms

C Ratledge, JP Wynn - Advances in applied microbiology, 2002 - Elsevier
The concept of using microorganisms as sources of oils and fats has a long history. The
commercial opportunities of such processes have been continuously examined for nearly a …

Recent advances in the study of fatty acid desaturases from animals and lower eukaryotes

SL Pereira, AE Leonard, P Mukerji - Prostaglandins, Leukotrienes and …, 2003 - Elsevier
The biosynthesis of polyunsaturated fatty acids (PUFAs) in different organisms can involve a
variety of pathways, catalyzed by a complex series of desaturation and elongation steps. A …

The evolution of desaturases

P Sperling, P Ternes, TK Zank, E Heinz - Prostaglandins, Leukotrienes and …, 2003 - Elsevier
When considering the evolution of desaturases, several different aspects come into focus,
the most obvious ones being phylogenetic origins and differentiation of regioselectivities of …

The front-end desaturase: structure, function, evolution and biotechnological use

D Meesapyodsuk, X Qiu - Lipids, 2012 - Springer
Very long chain polyunsaturated fatty acids such as arachidonic acid (ARA, 20: 4n-6),
eicosapentaenoic acid (EPA, 20: 5n-3), docosapentaenoic acid (DPA, 22: 5n-3) and …

Mucor indicus: biology and industrial application perspectives: a review

K Karimi, A Zamani - Biotechnology advances, 2013 - Elsevier
Mucor indicus, one of the most important strains of zygomycetes fungi, has been the subject
of several studies since a couple of hundred years ago. This fungus, regarded as a non …

Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae

JA Chemler, Y Yan, MAG Koffas - Microbial Cell Factories, 2006 - Springer
Industrial biotechnology employs the controlled use of microorganisms for the production of
synthetic chemicals or simple biomass that can further be used in a diverse array of …

Improved γ-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases

Y Zhang, X Luan, H Zhang, V Garre, Y Song… - Microbial cell …, 2017 - Springer
Background γ-Linolenic acid (GLA) is important because of its nutritional value and
medicinal applications. Although the biosynthetic pathways of some plant and microbial GLA …

Membrane fatty acid desaturase: biosynthesis, mechanism, and architecture

NFAA Halim, MSM Ali, ATC Leow… - Applied Microbiology and …, 2022 - Springer
Fatty acid desaturase catalyzes the desaturation reactions by inserting double bonds into
the fatty acyl chain, producing unsaturated fatty acids, which play a vital part in the synthesis …

Enzymes for transgenic biosynthesis of long-chain polyunsaturated fatty acids

YS Huang, SL Pereira, AE Leonard - Biochimie, 2004 - Elsevier
Polyunsaturated fatty acids (PUFAs) are important for the normal development and function
of all organisms, and are essential in maintaining human health. Impaired PUFA metabolism …

Mucoralean fungi for sustainable production of bioethanol and biologically active molecules

B Satari, K Karimi - Applied microbiology and biotechnology, 2018 - Springer
Mucoralean fungi are suitable microorganisms for the sustainable production of food, fodder,
and fuels from inexpensive natural resources. Ethanol-producing Mucorales are particularly …