[HTML][HTML] Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications

Q Kang, C Yang - Redox biology, 2020 - Elsevier
Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …

[HTML][HTML] Pericytes, an overlooked player in vascular pathobiology

D Ferland-McCollough, S Slater, J Richard… - Pharmacology & …, 2017 - Elsevier
Pericytes are a heterogeneous population of cells located in the blood vessel wall. They
were first identified in the 19th century by Rouget, however their biological role and potential …

Pericyte loss in diseases

P Li, H Fan - Cells, 2023 - mdpi.com
Pericytes are specialized cells located in close proximity to endothelial cells within the
microvasculature. They play a crucial role in regulating blood flow, stabilizing vessel walls …

Aging is not a disease: distinguishing age-related macular degeneration from aging

D Ardeljan, CC Chan - Progress in retinal and eye research, 2013 - Elsevier
Age-related macular degeneration (AMD) is a disease of the outer retina, characterized most
significantly by atrophy of photoreceptors and retinal pigment epithelium accompanied with …

Molecular mechanisms of diabetic retinopathy, general preventive strategies, and novel therapeutic targets

SZ Safi, R Qvist, S Kumar… - BioMed research …, 2014 - Wiley Online Library
The growing number of people with diabetes worldwide suggests that diabetic retinopathy
(DR) and diabetic macular edema (DME) will continue to be sight threatening factors. The …

Diabetic retinopathy: Breaking the barrier

RS Eshaq, AMZ Aldalati, JS Alexander, NR Harris - Pathophysiology, 2017 - Elsevier
Diabetic retinopathy (DR) remains a major complication of diabetes and a leading cause of
blindness among adults worldwide. DR is a progressive disease affecting both type I and …

Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases

SA Kandarakis, C Piperi, F Topouzis… - Progress in retinal and …, 2014 - Elsevier
Advanced glycation end products (AGEs) have been implicated in vision loss associated
with macula degeneration, cataract formation, diabetic retinopathy and glaucoma. This …

Advanced glycation end products in diabetic retinopathy and phytochemical therapy

Q Kang, H Dai, S Jiang, L Yu - Frontiers in Nutrition, 2022 - frontiersin.org
Advanced glycation end products (AGEs) are generated by the nonenzymatic glycation of
proteins or lipids. Diabetic retinopathy (DR) is one common complication in patients with …

[HTML][HTML] ROS mediated antibacterial activity of photoilluminated riboflavin: a photodynamic mechanism against nosocomial infections

S Khan, M Rayis, A Rizvi, MM Alam, M Rizvi, I Naseem - Toxicology reports, 2019 - Elsevier
Nosocomial infections are a major threat to modern therapeutics. The major causative agent
of these infections is multidrug-resistant gram-negative bacteria, which impart high morbidity …

Advanced glycation end products induce human corneal epithelial cells apoptosis through generation of reactive oxygen species and activation of JNK and p38 MAPK …

L Shi, X Yu, H Yang, X Wu - PloS one, 2013 - journals.plos.org
Advanced Glycation End Products (AGEs) has been implicated in the progression of diabetic
keratopathy. However, details regarding their function are not well understood. In the …