[HTML][HTML] Association between periodontal pathogens and systemic disease

FQ Bui, CLC Almeida-da-Silva, B Huynh, A Trinh, J Liu… - Biomedical journal, 2019 - Elsevier
A growing body of literature suggests that there is a link between periodontitis and systemic
diseases. These diseases include cardiovascular disease, gastrointestinal and colorectal …

Mechanisms underlying the association between periodontitis and atherosclerotic disease

HA Schenkein, PN Papapanou, R Genco… - Periodontology …, 2020 - Wiley Online Library
Atherosclerosis is central to the pathology of cardiovascular diseases, a group of diseases in
which arteries become occluded with atheromas that may rupture, leading to different …

Oral inflammation and infection, and chronic medical diseases: implications for the elderly

FA Scannapieco, A Cantos - Periodontology 2000, 2016 - Wiley Online Library
Oral diseases, such as caries and periodontitis, not only have local effects on the dentition
and on tooth‐supporting tissues but also may impact a number of systemic conditions …

Infection and atherosclerosis: TLR-dependent pathways

B Li, Y Xia, B Hu - Cellular and Molecular Life Sciences, 2020 - Springer
Atherosclerotic vascular disease (ASVD) is a chronic process, with a progressive course
over many years, but it can cause acute clinical events, including acute coronary syndromes …

Active Invasion of Porphyromonas gingivalis and Infection-Induced Complement Activation in ApoE-/- Mice Brains

S Poole, SK Singhrao, S Chukkapalli… - Journal of …, 2014 - journals.sagepub.com
Periodontal disease is a polymicrobial inflammatory disease that leads to chronic systemic
inflammation and direct infiltration of bacteria/bacterial components, which may contribute to …

The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights

Y Li, M Zhu, Y Liu, B Luo, J Cui, L Huang… - Frontiers in …, 2022 - frontiersin.org
There is mounting evidence demonstrating that oral dysbiosis causes periodontal disease
and promotes the development of cardiovascular disease. The advancement of omics …

TGF-β (transforming growth factor-β) signaling protects the thoracic and abdominal aorta from angiotensin II-induced pathology by distinct mechanisms

SN Angelov, JH Hu, H Wei, N Airhart… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—The role of TGF-β (transforming growth factor-β) signaling in abdominal aortic
aneurysm (AAA) formation is controversial. Others reported that systemic blockade of TGF-β …

Neutrophil functions in periodontal homeostasis

R Cortés-Vieyra, C Rosales… - Journal of immunology …, 2016 - Wiley Online Library
Oral tissues are constantly exposed to damage from the mechanical effort of eating and to
microorganisms, mostly bacteria. In healthy gingiva tissue remodeling and a balance …

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

MC Carra, H Rangé, G Caligiuri… - Periodontology …, 2023 - Wiley Online Library
In spite of intensive research efforts driving spectacular advances in terms of prevention and
treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for …

The impact of periodontitis on vascular endothelial dysfunction

Q Li, X Ouyang, J Lin - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
Periodontitis, an oral inflammatory disease, originates from periodontal microbiota dysbiosis
which is associated with the dysregulation of host immunoinflammatory response. This …