[HTML][HTML] Mechanism-based inactivators of sirtuin 5: A focused structure–activity relationship study

TN Hansen, X Yuan, MSI Santana, CA Olsen - Bioorganic & Medicinal …, 2025 - Elsevier
Abstract Sirtuin 5 (SIRT5) is a lysine deacylase enzyme that cleaves negatively charged ε-N-
acyllysine posttranslational modifications, arising from short dicarboxylic acids. Inhibition of …