Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …

Herpes simplex virus type 1 (HSV-1) is a neuroinvasive human pathogen that has the ability
to infect and replicate within epithelial cells and neurons and establish a life-long latent …

Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2) produce lifelong infections
and are highly prevalent in the human population. Both viruses elicit numerous clinical …

Alzheimer's Disease (AD) is an aging-associated neurodegenerative disorder, threatening
millions of people worldwide. The onset and progression of AD can be accelerated by …

The assembly and egress of herpes simplex virus (HSV) is a complicated multistage process
that involves several different cellular compartments and the activity of many viral and …

Herpesviruses—ubiquitous pathogens that cause persistent infections—have some of the
most complex cell entry mechanisms. Entry of the prototypical herpes simplex virus 1 (HSV …

Herpes simplex virus type 1 (HSV‐1) is an important human pathogen with neurotropism.
Following lytic infection in mucosal or skin epithelium, life‐long latency is established mainly …

The advances in gene editing bring unprecedented opportunities in high throughput
functional genomics to animal research. Here we describe a genome wide CRISPR …

The tegument of herpesviruses is a highly complex structural layer between the
nucleocapsid and the envelope of virions. Tegument proteins play both structural and …

Extracellular vesicles (EVs) are involved in numerous processes during infections by both
enveloped and non-enveloped viruses. Among them, herpes simplex virus type-1 (HSV-1) …