Syncytia in fungi

AP Mela, AM Rico-Ramírez, NL Glass - Cells, 2020 - mdpi.com
Filamentous fungi typically grow as interconnected multinucleate syncytia that can be
microscopic to many hectares in size. Mechanistic details and rules that govern the …

Fungal cell death: the beginning of the end

AM Rico-Ramírez, AP Gonçalves, NL Glass - Fungal Genetics and Biology, 2022 - Elsevier
Death is an important part of an organism's existence and also marks the end of life. On a
cellular level, death involves the execution of complex processes, which can be classified …

A dialogue-like cell communication mechanism is conserved in filamentous ascomycete fungi and mediates interspecies interactions

H Haj Hammadeh, A Serrano… - Proceedings of the …, 2022 - National Acad Sciences
In many filamentous fungi, germinating spores cooperate by fusing into supracellular
structures, which develop into the mycelial colony. In the model fungus Neurospora crassa …

A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in Neurospora crassa allorecognition

TC Detomasi, AM Rico-Ramírez, RI Sayler… - elife, 2022 - elifesciences.org
Organisms require the ability to differentiate themselves from organisms of different or even
the same species. Allorecognition processes in filamentous fungi are essential to ensure …

Lineage-specific genes are clustered with HET-domain genes and respond to environmental and genetic manipulations regulating reproduction in Neurospora

Z Wang, YW Wang, T Kasuga, F Lopez-Giraldez… - PLoS …, 2023 - journals.plos.org
Lineage-specific genes (LSGs) have long been postulated to play roles in the establishment
of genetic barriers to intercrossing and speciation. In the genome of Neurospora crassa …

Highly conserved, but highly specific: somatic cell–cell fusion in filamentous fungi

A Fleißner, AG Oostlander, L Well - Current Opinion in Cell Biology, 2022 - Elsevier
The development of ascomycete fungal colonies involves cell–cell fusion at different growth
stages. In the model fungus Neurospora crassa, communication of two fusing cells is …

The Narrow Footprint of Ancient Balancing Selection Revealed by Heterokaryon Incompatibility Genes in Aspergillus fumigatus

B Auxier, J Zhang, FR Marquez… - Molecular Biology …, 2024 - academic.oup.com
In fungi, fusion between individuals leads to localized cell death, a phenomenon termed
heterokaryon incompatibility. Generally, the genes responsible for this incompatibility are …

Establishment of conidial fusion in the asexual fungus Verticillium dahliae as a useful system for the study of non-sexual genetic interactions

V Vangalis, M Knop, MA Typas, IA Papaioannou - Current genetics, 2021 - Springer
Cell-to-cell fusion is a fundamental biological process across the tree of life. In filamentous
fungi, somatic fusion (or anastomosis) is required for the normal development of their …

[HTML][HTML] The Bcvic1 and Bcvic2 vegetative incompatibility genes in Botrytis cinerea encode proteins with domain architectures involved in allorecognition in other …

S Arshed, MP Cox, RE Beever, SL Parkes… - Fungal Genetics and …, 2023 - Elsevier
Vegetative incompatibility is a fungal allorecognition system characterised by the inability of
genetically distinct conspecific fungal strains to form a viable heterokaryon and is controlled …

Permissiveness and competition within and between Neurospora crassa syncytia

AP Mela, NL Glass - Genetics, 2023 - academic.oup.com
A multinucleate syncytium is a common growth form in filamentous fungi. Comprehensive
functions of the syncytial state remain unknown, but it likely allows for a wide range of …