Significance: Both incidence and mortality rates of sepsis significantly increase with
advanced age, and the majority of sepsis patients are late middle-aged or older. With the …

Primary liver cancer is one of the leading causes of cancer-related deaths worldwide. China
has more than 55% liver cancer cases globally. The development of hepatocellular …

Background The effects of body mass index (BMI) on mortality of sepsis remain unknown,
since previous meta-analyses have reported conflicting results. Several observational …

Polygonatum sibiricum is a traditional medicinal and dietary plant of the family Liliaceae.
The main functional macromolecules of P. sibiricum are polysaccharides, which function in …

The efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is limited by
acute and chronic graft-versus-host disease (GVHD). The impact of obesity on allo-HSCT …

Neutrophil extracellular traps (NETs) immobilize pathogens during early stages of systemic
inflammation but as the reaction progresses they become detrimental to endothelial cells …

Objectives Expound upon priorities for basic/translational science identified in a recent
paper by a group of experts assigned by the Society of Critical Care Medicine and the …

Objective Disorders of lipid oxidation play an important role in organ damage, and lipid
metabolites are associated with inflammation and coagulation dysfunction in sepsis …

Obesity manifests itself with low-grade chronic inflammation that shapes immune responses
during infection. Albeit obese individuals are at risk of higher mortality due to comorbidities …

Patients with inflammatory liver diseases, particularly alcohol-associated liver disease and
metabolic dysfunction-associated fatty liver disease (MAFLD), have higher incidence of …