Aims Diabetic nephropathy is a major cause of chronic kidney disease and end-stage renal
failure worldwide. Dapagliflozin Sodium-glucose co-transporter 2 (SGLT2) inhibitor is a new …

Early detection and clinical interference are major challenges for the prevention of diabetic
nephropathy (DN) progression. This study investigated the effects of dapagliflozin, a sodium …

The present study was designed to investigate the nephroprotective effect of bromelain
against oxidative stress stimulated by aluminium chloride in rats. Rats were grouped as …

Purpose Matrix‐assisted laser desorption/ionization mass spectrometry imaging (MALDI‐
MSI) technology has advanced rapidly during recent years with the development of …

Most automated image segmentation approaches in histological analyses are either
developed or trained for a specific histological stain. In this paper, we propose and …

This study aimed to evaluate the anti-hyperglycemic and antioxidant role of Actinidia
deliciosa (kiwifruits) aqueous extract in streptozotocin-treated rats. Animals were distributed …

Aims/hypothesis Diabetic kidney disease (DKD) is the leading cause of chronic and end-
stage kidney disease in the USA and worldwide. Animal models have taught us much about …

Chronic kidney disease (CKD) is a worldwide health burden with increases risk of end-stage
renal function if left untreated. CKD induced in the context of metabolic syndrome (MS) …

Kidney disease progression can be affected by Na+ abundance. A key regulator of Na+
homeostasis is the ubiquitin ligase NEDD4-2 and its deficiency leads to increased Na+ …

Calcineurin inhibitors, such as Cyclosporin (CsA), are the mainstay of anti-rejection therapy
in solid organ transplants but can paradoxically induce progressive nephropathy …