The epigenome is dynamic and forged by epigenetic mechanisms, such as DNA
methylation, histone modifications, chromatin remodeling, and non-coding RNA species …

Congenital heart disease (CHD) is one of the major debilitating birth defects resulting in
significant impact on neonatal and child mortality globally. The etiology of CHD is complex …

Background The primary differentially methylated regions (DMRs) which are maternally
hypermethylated serve as imprinting control regions (ICRs) that drive monoallelic gene …

Genomic imprinting is an epigenetically-regulated process of central importance in
mammalian development and evolution. It involves multiple levels of regulation, with spatio …

Introduction Identifying genomic regions under selection is the most challenging issue for
improving important traits in animals. Few studies have focused on identifying genomic …

Background: The hypothalamic proopiomelanocortin (Pomc) neurons act as first-order
sensors of systemic energy stores, providing signals that regulate caloric intake and energy …

This mini-review focuses on current knowledge regarding maternal regulation of the
paternal genome in early embryos of mammalian livestock species. Emphasis has been …

In mammals, imprinted genes often exist in the form of clusters in specific chromosome
regions. However, in pigs, genomic imprinting of a relatively few genes and clusters has …

Genomic imprinting refers to the expression of parent-specific genes in diploid mammalian
cells. MAGEL2 gene is a maternally imprinted gene that has been identified in mice and …

In addition to the well-established DNA-based inheritance, phenotypes can also be
transmitted across generations without changes in the DNA sequence, a process referred to …