Glycoproteomics
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …
proteins and is a crucial protein modification in health and disease. The aim of …
[HTML][HTML] Biodegradation of polyethylene and polystyrene: From microbial deterioration to enzyme discovery
The global production of plastics has continuously been soaring over the last decades due
to their extensive use in our daily life and in industries. Although synthetic plastics offer great …
to their extensive use in our daily life and in industries. Although synthetic plastics offer great …
Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity
Ulcerative colitis (UC) is driven by disruptions in host–microbiota homoeostasis, but current
treatments exclusively target host inflammatory pathways. To understand how host …
treatments exclusively target host inflammatory pathways. To understand how host …
Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section
E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …
MS) techniques has provided substantial insights into the field of structural biology over the …
[HTML][HTML] Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier
Multisystem inflammatory syndrome in children (MIS-C) occurs during or recently following
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and is …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and is …
[HTML][HTML] Dual proteome-scale networks reveal cell-specific remodeling of the human interactome
Thousands of interactions assemble proteins into modules that impart spatial and functional
organization to the cellular proteome. Through affinity-purification mass spectrometry, we …
organization to the cellular proteome. Through affinity-purification mass spectrometry, we …
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
J Zhang, CM Simpson, J Berner, HB Chong, J Fang… - Cell, 2023 - cell.com
Multiple anticancer drugs have been proposed to cause cell death, in part, by increasing the
steady-state levels of cellular reactive oxygen species (ROS). However, for most of these …
steady-state levels of cellular reactive oxygen species (ROS). However, for most of these …
A critical review of bottom-up proteomics: the good, the bad, and the future of this field
EJ Dupree, M Jayathirtha, H Yorkey, M Mihasan… - Proteomes, 2020 - mdpi.com
Proteomics is the field of study that includes the analysis of proteins, from either a basic
science prospective or a clinical one. Proteins can be investigated for their abundance …
science prospective or a clinical one. Proteins can be investigated for their abundance …
MSBooster: improving peptide identification rates using deep learning-based features
Peptide identification in liquid chromatography-tandem mass spectrometry (LC-MS/MS)
experiments relies on computational algorithms for matching acquired MS/MS spectra …
experiments relies on computational algorithms for matching acquired MS/MS spectra …
Parallelized acquisition of orbitrap and astral analyzers enables high-throughput quantitative analysis
HI Stewart, D Grinfeld, A Giannakopulos… - Analytical …, 2023 - ACS Publications
The growing trend toward high-throughput proteomics demands rapid liquid
chromatography–mass spectrometry (LC–MS) cycles that limit the available time to gather …
chromatography–mass spectrometry (LC–MS) cycles that limit the available time to gather …