Orchestration of MUC2—The key regulatory target of gut barrier and homeostasis: A review

Y Liu, Z Yu, L Zhu, S Ma, Y Luo, H Liang, Q Liu… - International Journal of …, 2023 - Elsevier
The gut mucosa of human is covered by mucus, functioning as a crucial defense line for the
intestine against external stimuli and pathogens. Mucin2 (MUC2) is a subtype of secretory …

Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease

M Xiu, Y Wang, D Yang, X Zhang, Y Dai… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic and life-treating inflammatory disease that
can occur in multiple parts of the human intestine and has become a worldwide problem …

Orally administered CLA ameliorates DSS-induced colitis in mice via intestinal barrier improvement, oxidative stress reduction, and inflammatory cytokine and gut …

Y Chen, B Yang, RP Ross, Y Jin… - Journal of agricultural …, 2019 - ACS Publications
Dietary supplementation with conjugated linoleic acid (CLA) has been reported to alleviate
the effect of colitis in mice, but the mechanisms involved need further exploration. The study …

Inhibitory effect of Bifidobacterium bifidum ATCC 29521 on colitis and its mechanism

AU Din, A Hassan, Y Zhu, K Zhang, Y Wang, T Li… - The Journal of nutritional …, 2020 - Elsevier
Probiotics are known to be beneficial in preventing different diseases in model animals,
including inflammatory bowel disease. However, there are few studies on probiotics related …

[HTML][HTML] Melatonin promotes gut anti-oxidative status in perinatal rat by remodeling the gut microbiome

X Yi, R Cai, W Shaoyong, G Wang, W Yan, Z He, R Li… - Redox biology, 2023 - Elsevier
Gut health is important for nutrition absorption, reproduction, and lactation in perinatal and
early weaned mammals. Although melatonin functions in maintaining circadian rhythms and …

Intestinal-targeted nanotubes-in-microgels composite carriers for capsaicin delivery and their effect for alleviation of Salmonella induced enteritis

Y Yuan, Y Liu, Y He, B Zhang, L Zhao, S Tian, Q Wang… - Biomaterials, 2022 - Elsevier
Salmonella is a word-wide food-borne pathogen, which can cause severe enteritis and
intestinal microbiota imbalance. Capsaicin (Cap), a food-based bioactive ingredient, has …

Bacillus subtilis programs the differentiation of intestinal secretory lineages to inhibit Salmonella infection

Q Hou, J Jia, J Lin, L Zhu, S Xie, Q Yu, Y Li - Cell Reports, 2022 - cell.com
The role of intestinal microbiota on fate determination of intestinal epithelial cells has not
been extensively examined. In this study, we explore the effect of Bacillus subtilis on …

Alleviation effects of Bifidobacterium breve on DSS-induced colitis depends on intestinal tract barrier maintenance and gut microbiota modulation

Y Chen, Y Jin, C Stanton, R Paul Ross, J Zhao… - European Journal of …, 2021 - Springer
Purpose The study aimed to investigate the discrepancy and potential mechanisms of
different CLA-producing B. breve on dextran sulphate sodium (DSS)-induced colitis …

Lactobacillus rhamnosus GG supplementation modulates the gut microbiota to promote butyrate production, protecting against deoxynivalenol exposure in nude mice

R Lin, Y Sun, P Mu, T Zheng, H Mu, F Deng… - Biochemical …, 2020 - Elsevier
Deoxynivalenol (DON) is the most common mycotoxin in grains, and DON exposure causes
gastrointestinal inflammation and systemic immunosuppression. The immunosuppression …

Nuciferine alleviates intestinal inflammation by inhibiting MAPK/NF-κB and NLRP3/Caspase 1 pathways in vivo and in vitro

U Kulhari, S Kundu, MN Mugale, BD Sahu - International …, 2023 - Elsevier
Nuciferine (NCF) is an aporphine alkaloid and a principal bioactive constituent in the lotus
plant. Herewith, we investigated the potential anti-inflammatory effect and underlying …