With the aging of the global population, the incidence of musculoskeletal diseases has been
increasing, seriously affecting people's health. As people age, the microenvironment within …

Lipids are biological molecules that play vital roles in all living organisms. They perform
many cellular functions, such as 1) forming cellular and subcellular membranes, 2) storing …

The pathophysiology of osteoporosis (OP) is influenced by exposure to nonessential harmful
metals and insufficient or excessive intake of necessary metals. Investigating multiple …

Background: Osteoporosis, which is a bone disease, is characterized by low bone mineral
density and an increased risk of fractures. The heel bone mineral density is often used as a …

Primary Hyperparathyroidism (PHPT) is characterized by excessive parathormone (PTH)
secretion and disrupted calcium homeostasis. Untargeted metabolomics offers a valuable …

This paper reviews the application of metabolomics in the early diagnosis of osteoporosis in
recent years. The authors searched electronic databases for the keywords “metabolomics”,“ …

Introduction Global aging has made osteoporosis an increasingly serious public health
problem. Osteoporotic fractures seriously affect the quality of life of patients and increase …

Objective: To investigate the relationships of multiple lipid metabolism indicators and bone
turnover markers (BTMs) with bone mineral density (BMD) and osteoporosis, in order to …

Osteoporosis is a common skeletal disorder characterized by an imbalance between bone
resorption and formation, exhibiting a higher prevalence in women compared with men …

Osteoporosis (OP) is a prevalent skeletal disorder characterized by decreased bone mineral
density (BMD) and increased fracture risk. The advancements in omics technologies …