OBJECTIVES: Compare reported rates of mood-shifts from major depression to
mania/hypomania/mixed-states during antidepressant (AD)-treatment and rates of …

Background: The prevalence, characteristics and implications of excessive arousal-
activation in children and adolescents treated with antidepressants for specific illnesses …

Several factors have amplified concern about the possibility that antidepressant medication
may contribute to induction of pediatric mania. These include the high rate of antidepressant …

Objective Several controlled trials have demonstrated the efficacy and safety of Fluoxetine in
children and adolescents with Obsessive-Compulsive Disorder (OCD), but there is no …

OBJECTIVE: This study investigated how study type, mean patient age, and amount of
contact with research staff affected response rates to medication and placebo in acute …

Objective We aimed to explore whether the prevalence of manic switch was underestimated
in randomized controlled trials (RCT s) compared to observational studies (OS s). Method …

Objective: The aim of this study was to estimate the incidence of treatment‐emergent
mania/hypomania (TEMH) and to describe the clinical characteristics of patients with major …

To assess the effectiveness and tolerability of citalopram for the acute treatment of children
and adolescents suffering from depression and/or anxiety disorders. As much as 78 …

Objective: To review the basic pharmacology and published literature regarding
escitalopram and citalopram in child and adolescent depression. Methods: A literature …

This meta-analysis aims to inform clinical practice of treatment strategies for adolescents
with major depressive disorder (MDD). The efficacy of three empirically validated treatments …