Kratom, or Mitragyna, is a tropical plant indigenous to Southeast Asia, with unique
pharmacological properties. It is commonly consumed by preparing the leaves into …

The abuse of psychotropic substances is a well-known phenomenon, and many of them are
usually associated with ancestral traditions and home remedies. This is the case of …

Background: Mitragyna speciosa (kratom) is increasingly used in the United States for its
pharmacological effects. Kratom's relative novelty makes for a dynamic situation, such that …

Background Mitragyna speciosa, referred to as “kratom”, is increasingly used in the United
States for self-treating pain, psychiatric, and substance use disorder symptoms. It is used by …

There is limited understanding regarding kratom use among US adults. Although
motivations for use are increasingly understood, typical kratom doses, threshold of (low and …

Abstract Purpose of Review This systematic review examines case reports of kratom
physical dependence or addiction, focusing on assessment, diagnosis, and treatment …

Abstract Purpose of Review This work aims to provide an up-to-date review of the preclinical
and clinical scientific literature on the therapeutic value of kratom to better understand the …

Drugs are regulated in the United States (US) by the Controlled Substances Act (CSA) if
assessment of their abuse potential, including public health risks, show such control is …

Parallel to the growing use of kratom, there is a wealth of evidence from self-report,
preclinical, and early clinical studies on therapeutic benefits of its alkaloids in particular for …

Abstract Kratom (Mitragyna speciosa Korth.) is a tree native to Southeast Asia with dose-
dependent stimulant and opioid-like effects. Dried, powdered leaf material is among the …