To serve and to protect: the role of decidual innate immune cells on human pregnancy

J Zhang, C Dunk, AB Croy, SJ Lye - Cell and tissue research, 2016 - Springer
The maternal–fetal interface undergoes dynamic changes that promote successful
development of the embryo/fetal allograft during pregnancy. This immune privilege of the …

[HTML][HTML] Composition, development, and function of uterine innate lymphoid cells

JM Doisne, E Balmas, S Boulenouar… - The Journal of …, 2015 - journals.aai.org
Innate lymphoid cells (ILCs), including NK cells, contribute to barrier immunity and tissue
homeostasis. In addition to the role of uterine NK cells in placentation and fetal growth, other …

Innate Lymphoid Cells in Response to Intracellular Pathogens: Protection Versus Immunopathology

AA Korchagina, E Koroleva… - Frontiers in Cellular and …, 2021 - frontiersin.org
Innate lymphoid cells (ILCs) are a heterogeneous group of cytokine-producing lymphocytes
which are predominantly located at mucosal barrier surfaces, such as skin, lungs, and …

The ETS1 transcription factor is required for the development and cytokine-induced expansion of ILC2

EC Zook, K Ramirez, X Guo, G van der Voort… - Journal of Experimental …, 2016 - rupress.org
Group 2 innate lymphoid cells (ILC2s) are a subset of ILCs that play a protective role in the
response to helminth infection, but they also contribute to allergic lung inflammation. Here …

Redefining the role of lymphotoxin beta receptor in the maintenance of lymphoid organs and immune cell homeostasis in adulthood

Y Shou, E Koroleva, CM Spencer, SA Shein… - Frontiers in …, 2021 - frontiersin.org
Lymphotoxin beta receptor (LTβR) is a promising therapeutic target in autoimmune and
infectious diseases as well as cancer. Mice with genetic inactivation of LTβR display multiple …

Immune circuits to shape natural killer cells in cancer

I Mattiola - Cancers, 2021 - mdpi.com
Simple Summary Natural killer (NK) cells are circulating innate lymphocytes endowed with
antitumoral functions. NK cells are the innate counterpart of effector T cells and among the …

Pregnancy associated with Systemic Lupus Erythematosus: Immune tolerance in pregnancy and its deficiency in Systemic Lupus Erythematosus—An immunological …

C Gluhovschi, G Gluhovschi, L Petrica… - Journal of …, 2015 - Wiley Online Library
Pregnancy is a physiological condition that requires immune tolerance to the product of
conception. Systemic lupus erythematosus (SLE) is a disease with well‐represented …

Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin beta receptor signaling

X Feng, R Sun, M Lee, X Chen, S Guo, H Geng… - Elife, 2023 - elifesciences.org
Acute lymphoblastic and myeloblastic leukemias (ALL and AML) have been known to modify
the bone marrow microenvironment and disrupt non-malignant hematopoiesis. However, the …

Characterization of lymphopenia in patients with MS treated with dimethyl fumarate and fingolimod

M Nakhaei-Nejad, D Barilla, CH Lee… - Neurology …, 2017 - AAN Enterprises
Objective: Lymphopenia is a common occurrence of disease-modifying therapies (DMTs) for
relapsing-remitting MS (RRMS). The aim of this study was to dissect the prevalence of …

NK cells are biologic and biochemical targets of 6-mercaptopurine in Crohn's disease patients

S Yusung, D McGovern, L Lin, D Hommes… - Clinical …, 2017 - Elsevier
NK cells, which contribute to immune defense against certain viral infections and neoplasia,
are emerging as modifiers of chronic immunologic diseases including transplant rejection …