Smoking increases mortality from all causes and has a crucial role in atherosclerotic
cardiovascular disease (ASCVD). Active smoking and secondhand smoke exposure …

Endothelial dysfunction is one of the initial steps in the pathogenesis of atherosclerosis and
development of cardiovascular disease in patients with diabetes mellitus. Several risk …

Smoking represents one of the most important preventable risk factors for the development
of atherosclerosis. The present review aims at providing a comprehensive summary of …

Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and
cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early …

Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …

The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this
property accounts for all its known functions. As an electron donor, vitamin C is a potent …

PART I THE ENDOTHELIUM has long been viewed as an inert cellophane-like membrane
that lines the circulatory system with its primary essential function being the maintenance of …

Although vitamin E has been known as an essential nutrient for reproduction since 1922, we
are far from understanding the mechanisms of its physiological functions. Vitamin E is the …

The current recommended dietary allowance (RDA) for vitamin C for adult nonsmoking men
and women is 60 mg/d, which is based on a mean requirement of 46 mg/d to prevent the …