Early-Onset Colorectal Cancer Early-onset disease (at< 50 years of age) accounts for 10%
of colorectal cancer cases, and the incidence is increasing, particularly in high-income …

Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Background Combating viral hepatitis is part of the UN Sustainable Development Goals
(SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector …

Despite strong evidence of effectiveness, colorectal cancer (CRC) screening remains
underused. Currently, there are several options for CRC screening, each with its own …

Background Colorectal cancer is the third most diagnosed cancer in adults in the United
States. Early detection could prevent more than 90% of colorectal cancer–related deaths, yet …

As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …

In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

Importance Colorectal cancer is the third leading cause of cancer death for both men and
women, with an estimated 52 980 persons in the US projected to die of colorectal cancer in …

Colorectal cancer (CRC) is the third most common cancer in men and women in the United
States. CRC screening efforts are directed toward removal of adenomas and sessile …

Background Mounting evidence has demonstrated the vital importance of tumor-associated
macrophages (TAMs) and exosomes in the formation of the premetastatic niche. However …