Caspase‐8: A key protein of cross‐talk signal way in “PANoptosis” in cancer

M Jiang, L Qi, L Li, Y Wu, D Song… - International journal of …, 2021 - Wiley Online Library
Cysteinyl aspartate specific proteinase (Caspase)‐8 has long been considered a promoter
of apoptosis and part of the mechanism by which cytotoxic drugs kill cancer cells. With the …

Aloe‐emodin: a review of its pharmacology, toxicity, and pharmacokinetics

X Dong, Y Zeng, Y Liu, L You, X Yin… - Phytotherapy …, 2020 - Wiley Online Library
Aloe‐emodin is a naturally anthraquinone derivative and an active ingredient of Chinese
herbs, such as Cassia occidentalis, Rheum palmatum L., Aloe vera, and Polygonum …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …

Phenolic Constituents, Antioxidant and Preliminary Antimycoplasmic Activities of Leaf Skin and Flowers of Aloe vera (L.) Burm. f. (syn. A. barbadensis Mill.) from the …

A López, MS De Tangil, O Vega-Orellana, AS Ramírez… - Molecules, 2013 - mdpi.com
The methanol extracts of leaf skins and flowers of Aloe vera from the Canary Islands were
analyzed for their phenolic profiles and screened for their antioxidant and antimycoplasmic …

Quinones derived from plant secondary metabolites as anti-cancer agents

JJ Lu, JL Bao, GS Wu, WS Xu… - Anti-Cancer Agents …, 2013 - ingentaconnect.com
Quinones are plant-derived secondary metabolites that present some anti-proliferation and
anti-metastasis effects in various cancer types both in vitro and in vivo. This review focuses …

Anticancer potential of emodin

SC Hsu, JG Chung - BioMedicine, 2012 - Elsevier
Abstract Traditional Chinese Medicine (TCM) is widely used in clinical research due to its
low toxicity, low number of side effects, and low cost. Many components of common fruits …

Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular …

K Gong, C Chen, Y Zhan, Y Chen, Z Huang… - Journal of Biological …, 2012 - ASBMB
Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the broadly used Chinese
medicinal herb Stephaniae tetrandrae, exhibits potent antitumor effects and has the potential …

Targeting reactive oxygen species in cancer via Chinese herbal medicine

Q Qian, W Chen, Y Cao, Q Cao, Y Cui… - … Medicine and Cellular …, 2019 - Wiley Online Library
Recently, reactive oxygen species (ROS), a class of highly bioactive molecules, have been
extensively studied in cancers. Cancer cells typically exhibit higher levels of basal ROS than …

Advances in understanding the role of aloe emodin and targeted drug delivery systems in cancer

G Şeker Karatoprak, E Küpeli Akkol… - Oxidative Medicine …, 2022 - Wiley Online Library
Cancer is one of the important causes of death worldwide. Despite remarkable
improvements in cancer research in the past few decades, several cancer patients still …

Anti-cancer effects of aloe-emodin: a systematic review

B Sanders, AM Ray, S Goldberg… - Journal of clinical …, 2017 - pmc.ncbi.nlm.nih.gov
Background: Anthraquinones are a possible treatment option for oncological patients due to
their anti-cancer properties. Cancer patients often exhaust a plethora of resources that …