Immune-related adverse events of checkpoint inhibitors

M Ramos-Casals, JR Brahmer, MK Callahan… - Nature reviews Disease …, 2020 - nature.com
Cancer immunotherapies have changed the landscape of cancer treatment during the past
few decades. Among them, immune checkpoint inhibitors, which target PD-1, PD-L1 and …

Management of immune-related adverse events in patients treated with immune checkpoint inhibitor therapy: ASCO guideline update

BJ Schneider, J Naidoo, BD Santomasso… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To increase awareness, outline strategies, and offer guidance on the
recommended management of immune-related adverse events (irAEs) in patients treated …

Skin cancer: Primary, secondary, and tertiary prevention. Part II.

KD Rojas, ME Perez, MA Marchetti, AJ Nichols… - Journal of the American …, 2022 - Elsevier
Skin cancer is the most commonly diagnosed cancer worldwide. Understanding the natural
history of skin cancer will provide a framework for the creation of prevention and control …

[HTML][HTML] Persistent immune-related adverse events after cessation of checkpoint inhibitor therapy: prevalence and impact on patients' health-related quality of life

TU Schulz, S Zierold, MM Sachse, G Pesch… - European Journal of …, 2022 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) may induce persistent immune-
related adverse events (irAEs). We investigated persistent irAEs and implications on …

Autoimmune complications of immunotherapy: pathophysiology and management

KK Chan, AR Bass - bmj, 2020 - bmj.com
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target inhibitory
molecules, such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell …

Immune checkpoint-mediated psoriasis: A multicenter European study of 115 patients from the European Network for Cutaneous Adverse Event to Oncologic Drugs …

V Nikolaou, V Sibaud, D Fattore, P Sollena… - Journal of the American …, 2021 - Elsevier
Background Immune checkpoint inhibitor (ICI)–mediated psoriasis poses significant
diagnostic and therapeutic challenges. Objective To report data on ICI-mediated psoriasis …

Evolving landscape of metastatic cancer survivorship: reconsidering clinical care, policy, and research priorities for the modern era

J Lai-Kwon, S Heynemann, NH Hart… - Journal of Clinical …, 2023 - ascopubs.org
An individual may be considered a cancer survivor from diagnosis through the balance of
their life. 1 In contrast to those with early-stage cancer, survivorship care for people with …

Cutaneous immune‐related adverse events in patients with melanoma treated with checkpoint inhibitors

A Gault, AE Anderson, R Plummer… - British Journal of …, 2021 - academic.oup.com
Checkpoint inhibitor (CPI) therapy has vastly improved long‐term outcomes in metastatic
malignant melanoma (MMM). Therapy takes the form of monoclonal antibody infusions that …

[HTML][HTML] Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem

K Poels, SIM Neppelenbroek, MJ Kersten… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Antibody-mediated blockade of co-inhibitory molecules such as cytotoxic T lymphocyte-
associated protein 4, PD1 and PDL1 elicits potent antitumor responses and improves the …

Survivorship outcomes in patients treated with immune checkpoint inhibitors: a scoping review

DC Güven, MSY Thong, V Arndt - Journal of Cancer Survivorship, 2024 - Springer
Abstract Background Immune checkpoint inhibitors (ICIs) have become a central part of
cancer care. However, the survivorship outcomes in patients treated with ICIs are …