New Insights into the Cooperativity and Dynamics of Dimeric Enzymes

KW Chen, TY Sun, YD Wu - Chemical Reviews, 2023 - ACS Publications
A survey of protein databases indicates that the majority of enzymes exist in oligomeric
forms, with about half of those found in the UniProt database being homodimeric …

Plant monounsaturated fatty acids: Diversity, biosynthesis, functions and uses

S Kazaz, R Miray, L Lepiniec, S Baud - Progress in lipid research, 2022 - Elsevier
Monounsaturated fatty acids are straight-chain aliphatic monocarboxylic acids comprising a
unique carbon‑carbon double bond, also termed unsaturation. More than 50 distinct …

Plasmalogens and photooxidative stress signaling in myxobacteria, and how it unmasked CarF/TMEM189 as the Δ1′-desaturase PEDS1 for human plasmalogen …

S Padmanabhan, AJ Monera-Girona… - Frontiers in Cell and …, 2022 - frontiersin.org
Plasmalogens are glycerophospholipids with a hallmark sn-1 vinyl ether bond that endows
them with unique physical-chemical properties. They have proposed biological roles in …

Tools of the ethylene trade: a chemical kit to influence ethylene responses in plants and its use in agriculture

T Depaepe, D Van Der Straeten - Small Methods, 2020 - Wiley Online Library
The simplest unsaturated hydrocarbon, ethylene or ethene, is one of the most widely
produced organic chemicals worldwide. It serves as a building block for various materials …

Amino acid change in an orchid desaturase enables mimicry of the pollinator's sex pheromone

KEM Sedeek, E Whittle, D Guthörl, U Grossniklaus… - Current Biology, 2016 - cell.com
Mimicry illustrates the power of selection to produce phenotypic convergence in biology [1].
A striking example is the imitation of female insects by plants that are pollinated by sexual …

Monitoring ethylene in plants: genetically encoded reporters and biosensors

JP Fernandez‐Moreno, AN Stepanova - Small Methods, 2020 - Wiley Online Library
Phytohormone ethylene regulates numerous aspects of plant physiology, from fruit ripening
to pathogen responses. The molecular basis of ethylene biosynthesis and action has been …

Quaternary structure of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) controls its activity

Y Yang, I Davis, T Matsui, I Rubalcava, A Liu - Journal of Biological …, 2019 - ASBMB
α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) plays an important
role in l-tryptophan degradation via the kynurenine pathway. ACMSD forms a homodimer …

Chloride promotes refolding of active Vibrio alkaline phosphatase through an inactive dimeric intermediate with an altered interface

JG Hjörleifsson, B Ásgeirsson - FEBS Open bio, 2019 - Wiley Online Library
Most enzymes are homodimers or higher order multimers. Cold‐active alkaline phosphatase
from Vibrio splendidus (VAP) transitions into a dimer with very low activity under mild …

Identification and Functional Analysis of Acyl-Acyl Carrier Protein Δ9 Desaturase from Nannochloropsis oceanica

R Yang, H Wang, L Zhu, L Zhu, T Liu, D Zhang - Journal of Microbiology, 2023 - Springer
The oleaginous marine microalga Nannochloropsis oceanica strain IMET1 has attracted
increasing attention as a promising photosynthetic cell factory due to its unique excellent …

Catalytic mechanisms underlying fungal fatty acid desaturases activities

J Wu, C Wu, C Rong, J Tian, N Jiang, R Wu… - Critical Reviews in …, 2023 - Taylor & Francis
Polyunsaturated fatty acids (PUFAs) have beneficial roles in a variety of human pathologies
and disorders. Owing to the limited source of PUFAs in animals and plants, microorganisms …