Understanding the concept of network hubs and their role in brain disease is now rapidly
becoming important for clinical neurology. Hub nodes in brain networks are areas highly …

Functional magnetic resonance imaging research employing regional homogeneity (ReHo)
analysis has uncovered aberrant local brain connectivity in individuals with mild cognitive …

The recent advances in neuroimaging technology allow us to understand how the human
brain is wired in vivo and how functional activity is synchronized across multiple regions …

Previous studies have established that neurodegenerative disease such as Alzheimer's
disease (AD) is a disconnection syndrome, where the neuropathological burdens often …

Emerging research indicates that the degenerative biomarkers associated with Alzheimer's
disease (AD) exhibit a non-random distribution within the cerebral cortex, instead following …

Tremendous efforts have been made to investigate stereotypical patterns of tau aggregates
in Alzheimer's disease (AD), current positron emission tomography (PET) technology lacks …

Background Alzheimer's disease (AD) is a heterogeneous, multifactorial neurodegenerative
disorder characterized by three neurobiological factors beta‐amyloid, pathologic tau, and …