Understanding and preventing the global increase of inflammatory bowel disease

GG Kaplan, SC Ng - Gastroenterology, 2017 - Elsevier
The inflammatory bowel diseases (IBDs) are contemporary conditions of industrialized
societies. The prevalence of IBD continues to increase steadily in Western countries, and …

Systematic review: the gut microbiome and its potential clinical application in inflammatory bowel disease

L Aldars-Garcia, M Chaparro, JP Gisbert - Microorganisms, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract. It is well established that the gut microbiome has a profound impact on …

Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography

M Deschasaux, KE Bouter, A Prodan, E Levin… - Nature medicine, 2018 - nature.com
Trillions of microorganisms inhabit the human gut and are regarded as potential key factors
for health,. Characteristics such as diet, lifestyle, or genetics can shape the composition of …

Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers

Z Dai, OO Coker, G Nakatsu, WKK Wu, L Zhao, Z Chen… - Microbiome, 2018 - Springer
Background Alterations of gut microbiota are associated with colorectal cancer (CRC) in
different populations and several bacterial species were found to contribute to the …

Gut microbiome: what we do and don't know

GA Cresci, E Bawden - Nutrition in Clinical Practice, 2015 - Wiley Online Library
Within the last decade, research regarding the human gut microbiome has exploded. While
the gastrointestinal tract was once regarded simply as a digestive organ, new technologies …

Application of multivariate statistical techniques in microbial ecology

O Paliy, V Shankar - Molecular ecology, 2016 - Wiley Online Library
Recent advances in high‐throughput methods of molecular analyses have led to an
explosion of studies generating large‐scale ecological data sets. In particular, noticeable …

[HTML][HTML] Role of antibiotics for treatment of inflammatory bowel disease

O Nitzan, M Elias, A Peretz, W Saliba - World journal of …, 2016 - ncbi.nlm.nih.gov
Inflammatory bowel disease is thought to be caused by an aberrant immune response to gut
bacteria in a genetically susceptible host. The gut microbiota plays an important role in the …

Gut microbiota offers universal biomarkers across ethnicity in inflammatory bowel disease diagnosis and infliximab response prediction

Y Zhou, ZZ Xu, Y He, Y Yang, L Liu, Q Lin, Y Nie, M Li… - …, 2018 - Am Soc Microbiol
Gut microbiota dysbiosis contributes to the onset and perpetuation of inflammatory bowel
disease (IBD). Given that gut microbiotas vary across geography and ethnicity, it remains …

Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta‐Analysis and Systematic Review of the Literature

Y Cao, J Shen, ZH Ran - Gastroenterology research and …, 2014 - Wiley Online Library
Background. Laboratory data suggests a reduction of Faecalibacterium prausnitzii (F.
prausnitzii) is confirmed both in fecal samples in inflammatory bowel disease (IBD) patients …

Microbiota and mucosal defense in IBD: an update

EF Stange, BO Schroeder - Expert review of gastroenterology & …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel diseases (IBD) are on the rise worldwide. This review
covers the current concepts of the etiology of Crohn´ s disease and ulcerative colitis by …