Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

A Huber, F Dammeijer, JGJV Aerts… - Frontiers in …, 2018 - frontiersin.org
Dendritic cell (DC) based cancer immunotherapy aims at the activation of the immune
system, and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the …

Current approaches in dendritic cell generation and future implications for cancer immunotherapy

S Tuyaerts, JL Aerts, J Corthals, B Neyns… - Cancer Immunology …, 2007 - Springer
The discovery of tumor-associated antigens, which are either selectively or preferentially
expressed by tumors, together with an improved insight in dendritic cell biology illustrating …

Monocyte isolation techniques significantly impact the phenotype of both isolated monocytes and derived macrophages in vitro

MC Nielsen, MN Andersen, HJ Møller - Immunology, 2020 - Wiley Online Library
Monocyte‐derived macrophages (MDMs) generated from peripheral blood monocytes are
widely used to model human macrophages for in vitro studies. However, the possible impact …

Exosomal LGALS9 in the cerebrospinal fluid of glioblastoma patients suppressed dendritic cell antigen presentation and cytotoxic T-cell immunity

M Wang, Y Cai, Y Peng, B Xu, W Hui, Y Jiang - Cell death & disease, 2020 - nature.com
Glioblastoma multiforme (GBM) is highly invasive, with a high recurrence rate and limited
treatment options, and is the deadliest glioma. Exosomes (Exos) have attracted much …

High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays

N Cermak, S Olcum, FF Delgado, SC Wasserman… - Nature …, 2016 - nature.com
Methods to rapidly assess cell growth would be useful for many applications, including drug
susceptibility testing, but current technologies have limited sensitivity or throughput. Here we …

Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages

SB Yoon, YJ Lee, SK Park, HC Kim, H Bae… - Journal of …, 2009 - Elsevier
AIM OF THE STUDY: The root of Scutellaria baicalensis Georgi (Labiatae), also known as
Scutellariae Radix, possesses anticancer, antiviral, and anti-inflammatory properties. And it …

Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms of angiotensin II–induced inflammation

M Jurewicz, DH McDermott, JM Sechler… - Journal of the …, 2007 - journals.lww.com
The renin-angiotensin system (RAS) plays an important role in the regulation of
inflammation and in the progression of chronic kidney disease. Accumulation of …

Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells

T Eaves-Pyles, CA Allen, J Taormina… - International Journal of …, 2008 - Elsevier
Inflammatory diseases of the intestinal tract are a major health concern both in the United
States and around the world. Evidence now suggests that a new category of Escherichia …

Role of HLA-G and extracellular vesicles in renal cancer stem cell-induced inhibition of dendritic cell differentiation

C Grange, M Tapparo, S Tritta, MC Deregibus… - BMC cancer, 2015 - Springer
Background Tumor immune-escape has been related to the ability of cancer cells to inhibit T
cell activation and dendritic cell (DC) differentiation. We previously identified a tumor …

A protocol for rapid monocyte isolation and generation of singular human monocyte-derived dendritic cells

TQ Chometon, MS Siqueira, JC Sant´ anna… - PLoS …, 2020 - journals.plos.org
The monocyte-derived dendritic cells (moDCs) are a subset of dendritic cells widely used in
immunological studies as a convenient and easy approach after isolation of mononuclear …