Exosome: a review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications

Y Zhang, J Bi, J Huang, Y Tang, S Du… - International journal of …, 2020 - Taylor & Francis
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic
acids, proteins, lipids and other bioactive substances to play a role in the body's …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small …

KS Visan, RJ Lobb, S Ham, LG Lima… - Journal of …, 2022 - Wiley Online Library
Small extracellular vesicles (sEVs) provide major promise for advances in cancer
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …

Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages

K Asgarpour, Z Shojaei, F Amiri, J Ai… - Cell Communication and …, 2020 - Springer
Exosomes are extracellular vesicles characterized by their size, source, release mechanism
and contents. MicroRNAs (miRNAs) are single stranded non-coding RNAs transcribed from …

Elucidating methods for isolation and quantification of exosomes: a review

TK Kurian, S Banik, D Gopal, S Chakrabarti… - Molecular …, 2021 - Springer
Exosomes are the smallest extracellular vesicles present in most of the biological fluids.
They are found to play an important role in cell signaling, immune response, tumor …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Rapid and sensitive exosome detection with CRISPR/Cas12a

X Zhao, W Zhang, X Qiu, Q Mei, Y Luo, W Fu - Analytical and bioanalytical …, 2020 - Springer
Numerous studies have shown that exosomes are closely related to the pathogenesis of
various diseases, especially cancers. Therefore, a rapid and sensitive method for exosome …

Biological features of extracellular vesicles and challenges

Y Zeng, Y Qiu, W Jiang, J Shen, X Yao, X He… - Frontiers in Cell and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are vesicles with a lipid bilayer membrane on the outside, which
are widely found in various body fluids and contain biological macromolecules such as …

MicroRNAs in extracellular vesicles: sorting mechanisms, diagnostic value, isolation, and detection technology

D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in Bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

Recent advances and challenges in the recovery and purification of cellular exosomes

S Ayala‐Mar, J Donoso‐Quezada… - …, 2019 - Wiley Online Library
Exosomes are nanovesicles secreted by most cellular types that carry important biochemical
compounds throughout the body with different purposes, playing a preponderant role in …