Biosurfactants: Forthcomings and regulatory affairs in food-based industries

D Sharma, D Singh, GM Sukhbir-Singh… - Molecules, 2023 - mdpi.com
The terms discussed in this review—biosurfactants (BSs) and bioemulsifiers (BEs)—
describe surface-active molecules of microbial origin which are popular chemical entities for …

Physicochemical and electrochemical methods for determination of critical micelle concentrations of surfactants: a comprehensive review

MM Mabrouk, NA Hamed, FR Mansour - Monatshefte für Chemie …, 2022 - Springer
The interest in the determination of critical micelle concentrations (CMC) has been growing
for decades. The measurement of CMC is fundamental in many fields because surfactants …

Complex micellization behavior of the polysorbates Tween 20 and Tween 80

H Knoch, MH Ulbrich, JJ Mittag, J Buske… - Molecular …, 2021 - ACS Publications
Polysorbates (PSs, Tweens) are widely used surfactant products consisting of a sorbitan ring
connecting up to four ethylene oxide (EO) chains of variable lengths, one or more of which …

Surface tension and self-association properties of aqueous polysorbate 20 HP and 80 HP solutions: insights into protein stabilisation mechanisms

P Garidel, M Blech, J Buske, A Blume - Journal of Pharmaceutical …, 2021 - Springer
Objective Polysorbates 20 and 80 are the most used surfactants for the development of
parenteral protein formulations, because of their beneficial safety and stabilisation profile …

Development of a novel colloidal system enhancing the dispersibility of tocopherol nanoparticles in a nanoscale nutraceutical delivery system

S Yakoubi, I Kobayashi, K Uemura… - Colloids and Surfaces A …, 2023 - Elsevier
The aim of this study is to develop a new binary emulsifier system to be used as a surface-
active agent in a nanometric delivery system. The effect of the interaction between gum …

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80

N Glücklich, M Dwivedi, S Carle, J Buske… - International journal of …, 2020 - Elsevier
Two of the most widely used surfactants to stabilize biologicals against eg interfacial stress
are polysorbate 20 (PS20) and polysorbate 80 (PS80). In recent years, polysorbate …

Systematic evaluation of multifunctional paclitaxel-loaded polymeric mixed micelles as a potential anticancer remedy to overcome multidrug resistance

J Zhang, X Zhao, Q Chen, X Yin, X Xin, K Li, M Qiao… - Acta biomaterialia, 2017 - Elsevier
Multidrug resistance (MDR) of tumor cells is becoming the main reason for the failure of
chemotherapy and P-glycoprotein (P-gp) mediated drug efflux has demonstrated to be the …

In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery

LN Nodilo, M Perkušić, I Ugrina, D Špoljarić… - European journal of …, 2022 - Elsevier
In this work we present the development of in situ gelling nanosuspension as advanced form
for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling …

Fatty acid composition analysis in polysorbate 80 with high performance liquid chromatography coupled to charged aerosol detection

D Ilko, A Braun, O Germershaus, L Meinel… - European Journal of …, 2015 - Elsevier
The fatty acid (FA) composition of polysorbate 80 (PS80), a sorbitan oleic acid ester
copolymerized with about 20 mole of ethylene oxide, is typically characterized by gas …

End-to-end approach to surfactant selection, risk mitigation, and control strategies for protein-based therapeutics

AM Morales, A Sreedhara, J Buecheler, S Brosig… - The AAPS journal, 2022 - Springer
A survey performed by the AAPS Drug Product Handling community revealed a general,
mostly consensus, approach to the strategy for the selection of surfactant type and level for …