Reversible diffusion-weighted imaging lesions in acute ischemic stroke: a systematic review

N Nagaraja, JR Forder, S Warach, JG Merino - Neurology, 2020 - AAN Enterprises
Objectives To systematically review the literature for reversible diffusion-weighted imaging
(DWIR) lesions and to describe its prevalence, predictors, and clinical significance. Methods …

The back and forth of axonal injury and repair after stroke

JD Hinman - Current opinion in neurology, 2014 - journals.lww.com
Stroke-induced injury to axons occurs in three distinct phases each with a unique molecular
underpinning. A wealth of new data about the molecular organization and molecular …

Mechanical thrombectomy in ischemic stroke patients with alberta stroke program early computed tomography score 0–5

J Kaesmacher, P Chaloulos-Iakovidis, L Panos… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—If anterior circulation large vessel occlusion acute ischemic
stroke patients presenting with ASPECTS 0–5 (Alberta Stroke Program Early CT Score) …

The core/penumbra model: implications for acute stroke treatment and patient selection in 2021

JC Baron - European Journal of Neurology, 2021 - Wiley Online Library
Despite major advances in prevention, ischaemic stroke remains one of the leading causes
of death and disability worldwide. After centuries of nihilism and decades of failed …

How sustained is 24-hour diffusion-weighted imaging lesion reversal? Serial magnetic resonance imaging in a patient cohort thrombolyzed within 4.5 hours of stroke …

S Soize, M Tisserand, S Charron, G Turc… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Here, we assessed how sustained is reversal of the acute
diffusion lesion (RAD) observed 24 hours after intravenous thrombolysis, and the …

The story of an exceptional serine protease, tissue-type plasminogen activator (tPA)

M Hebert, F Lesept, D Vivien, R Macrez - Revue neurologique, 2016 - Elsevier
The only acute treatment of ischemic stroke approved by the health authorities is tissue
recombinant plasminogen activator (tPA)-induced thrombolysis. Under physiological …

e-ASPECTS derived acute ischemic volumes on non-contrast-enhanced computed tomography images

S Nagel, O Joly, J Pfaff… - … Journal of Stroke, 2020 - journals.sagepub.com
Background and purpose Validation of automatically derived acute ischemic volumes (AAIV)
from e-ASPECTS on non-contrast computed tomography (NCCT). Materials and methods …

Does diffusion lesion volume above 70 mL preclude favorable outcome despite post-thrombolysis recanalization?

M Tisserand, G Turc, S Charron, L Legrand, M Edjlali… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Whether to withhold recanalization treatment when the diffusion-
weighted imaging (DWI) lesion exceeds a given volume is unsettled. Our aim was to assess …

Tissue outcome prediction in hyperacute ischemic stroke: Comparison of machine learning models

J Benzakoun, S Charron, G Turc… - Journal of Cerebral …, 2021 - journals.sagepub.com
Machine Learning (ML) has been proposed for tissue fate prediction after acute ischemic
stroke (AIS), with the aim to help treatment decision and patient management. We compared …

Diffusion-weighted imaging lesion reversal in older patients with stroke treated with mechanical Thrombectomy

G Scopelliti, J Benzakoun, W Ben Hassen, M Bretzner… - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Diffusion-weighted imaging lesion reversal (DWIR) is frequently observed
after mechanical thrombectomy for acute ischemic stroke, but little is known about age …