The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Glioma is often referred to as one of the most dreadful central nervous system (CNS)-specific
tumors with rapidly-proliferating cancerous glial cells, accounting for nearly half of the brain …

Nature has always inspired robotic designs and concepts. It is conceivable that biomimic
nanorobots will soon play a prominent role in medicine. The “Terminator” in the science …

With the endothelium as its central unit, the blood–brain barrier (BBB) is a complex
multicellular structure separating the central nervous system (CNS) from the systemic …

This review summarises the evidence that chronic low grade inflammation triggers changes
that contribute to the mental and physical ill health of patients with major depression …

To maintain the homeostatic environment required for proper function of central nervous
system (CNS) neurons the endothelial cells of CNS microvessels tightly regulate the …

Background: Heart failure (HF) is a state of inappropriately sustained inflammation,
suggesting the loss of normal immunosuppressive mechanisms. Regulatory T-lymphocytes …

The central nervous system (CNS) is an immunologically privileged site to which access of
circulating immune cells is tightly controlled by the endothelial blood–brain barrier (BBB; see …

Each year about 650,000 Europeans die from stroke and a similar number lives with the
sequelae of multiple sclerosis (MS). Stroke and MS differ in their etiology. Although cause …

Abstract Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the
immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of …