The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment

AH Ashok, TR Marques, S Jauhar, MM Nour… - Molecular …, 2017 - nature.com
Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

Effects of early life stress on cognitive and affective function: an integrated review of human literature

P Pechtel, DA Pizzagalli - Psychopharmacology, 2011 - Springer
Rationale The investigation of putative effects of early life stress (ELS) in humans on later
behavior and neurobiology is a fast developing field. While epidemiological and …

Dopamine modulates the reward experiences elicited by music

L Ferreri, E Mas-Herrero, RJ Zatorre… - Proceedings of the …, 2019 - National Acad Sciences
Understanding how the brain translates a structured sequence of sounds, such as music,
into a pleasant and rewarding experience is a fascinating question which may be crucial to …

The Power of the Like in Adolescence: Effects of Peer Influence on Neural and Behavioral Responses to Social Media

LE Sherman, AA Payton, LM Hernandez… - Psychological …, 2016 - journals.sagepub.com
We investigated a unique way in which adolescent peer influence occurs on social media.
We developed a novel functional MRI (fMRI) paradigm to simulate Instagram, a popular …

[HTML][HTML] Acute social isolation evokes midbrain craving responses similar to hunger

L Tomova, KL Wang, T Thompson, GA Matthews… - Nature …, 2020 - nature.com
When people are forced to be isolated from each other, do they crave social interactions? To
address this question, we used functional magnetic resonance imaging to measure neural …

[HTML][HTML] States of curiosity modulate hippocampus-dependent learning via the dopaminergic circuit

MJ Gruber, BD Gelman, C Ranganath - Neuron, 2014 - cell.com
People find it easier to learn about topics that interest them, but little is known about the
mechanisms by which intrinsic motivational states affect learning. We used functional …

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

EA Ferenczi, KA Zalocusky, C Liston, L Grosenick… - Science, 2016 - science.org
INTRODUCTION The drive to seek and experience reward is conserved across species and,
in mammals, involves interactions between subcortical dopaminergic systems and limbic …

A randomized proof-of-mechanism trial applying the 'fast-fail'approach to evaluating κ-opioid antagonism as a treatment for anhedonia

AD Krystal, DA Pizzagalli, M Smoski, SJ Mathew… - Nature medicine, 2020 - nature.com
Abstract The National Institute of Mental Health (NIMH)'fast-fail'approach seeks to improve
too-often-misleading early-phase drug development methods by incorporating biomarker …

Anatomically distinct dopamine release during anticipation and experience of peak emotion to music

VN Salimpoor, M Benovoy, K Larcher, A Dagher… - Nature …, 2011 - nature.com
Music, an abstract stimulus, can arouse feelings of euphoria and craving, similar to tangible
rewards that involve the striatal dopaminergic system. Using the neurochemical specificity of …

Disclosing information about the self is intrinsically rewarding

DI Tamir, JP Mitchell - … of the National Academy of Sciences, 2012 - National Acad Sciences
Humans devote 30–40% of speech output solely to informing others of their own subjective
experiences. What drives this propensity for disclosure? Here, we test recent theories that …