Severe malaria is a medical emergency. It is a major cause of preventable childhood death
in tropical countries. Severe malaria justifies considerable global investment in malaria …

Malaria affected an estimated 216 million people causing 445,000 deaths in 2016. 1 This
reduced burden of disease and death is a result of more than a century of worldwide effort …

Infectious diseases may affect brain function and cause encephalopathy even when the
pathogen does not directly infect the central nervous system, known as infectious disease …

Despite decades of research on cerebral malaria (CM) there is still a paucity of knowledge
about what actual causes CM and why certain people develop it. Although sequestration of …

Over 90% of the world's severe and fatal Plasmodium falciparum malaria is estimated to
affect young children in sub-Sahara Africa, where it remains a common cause of hospital …

Zoonotic and vector-borne parasites are important preventable risk factors for epilepsy.
Three parasitic infections—cerebral malaria, Taenia solium cysticercosis and …

Severe malaria accounts for approximately 10% of all cases of imported malaria in France;
cases are mainly due to Plasmodium falciparum, while other Plasmodium species are …

Among all the parasitic diseases in humans, malaria is the most significant and malicious
one. The widespread species are Plasmodium falciparum and Plasmodium vivax, but the …

Summary Background Infection with Plasmodium falciparum leads to severe malaria and
death in approximately 400 000 children each year in sub-Saharan Africa. Blood transfusion …

Background African children with cerebral malaria and seizures caused Plasmodium
falciparum are at greater risk of poor outcomes including death and neurological sequelae …