Clefts of the lip and palate (CLP), the major causes of congenital facial malformation
globally, result from failure of fusion of the facial processes during embryogenesis. With a …

Palatogenesis is a complex and intricate process involving the formation of the palate
through various morphogenetic events highly dependent on the surrounding context. These …

Craniofacial anomalies are among the most common of birth defects. The pathogenesis of
craniofacial anomalies frequently involves defects in the migration, proliferation, and fate of …

Cranial neural crest (CNC) cells give rise to bone, cartilage, tendons, and ligaments of the
vertebrate craniofacial musculoskeletal complex, as well as regulate mesoderm-derived …

Background Orofacial clefts are the most common congenital malformation, but the global
burden and trends of orofacial clefts have not been comprehensively analysed. The aim of …

Orofacial cleft disorders, including cleft lip and/or palate (CL/P), are one of the most
frequently-occurring congenital disorders worldwide. The health issues of patients with CL/P …

The communication between myogenic cells and their surrounding connective tissues is
indispensable for muscle morphogenesis. During late embryonic development in mice …

Cleft lip with or without cleft palate (CL/P) is a common birth defect with a complex,
heterogeneous etiology. It is well established that common and rare sequence variants …

Objective Chewing, swallowing, and respiration are synchronized oropharyngeal functions.
This study aimed to analyze the dynamics and coordination during natural chewing and …

Objectives Mammalian palatogenesis is a highly regulated morphogenetic process to form
the intact roof of the oral cavity. Long noncoding RNAs (lncRNAs) and mRNAs participate in …