[PDF][PDF] Organization and expression of eucaryotic split genes coding for proteins
R Breathnach, P Chambon - Annual review of biochemistry, 1981 - researchgate.net
GLOBIN GENES Hemoglobin is composed of heme residues and two chains each of a-like
and, B-like globin polypeptides. Each type of chain is encoded by a family of genes under …
and, B-like globin polypeptides. Each type of chain is encoded by a family of genes under …
[HTML][HTML] A review of the molecular genetics of the human α-globin gene cluster
DURING THE relatively brief period in which molecular biology has been applied to human
disease, the structure, function, and synthesis of hemoglobin have been studied most …
disease, the structure, function, and synthesis of hemoglobin have been studied most …
[图书][B] The thalassaemia syndromes
DJ Weatherall, JB Clegg - 2008 - books.google.com
In the new edition of this successful and authoritative book, the thalassaemias are reviewed
in detail with respect to their clinical features, cellular pathology, molecular genetics …
in detail with respect to their clinical features, cellular pathology, molecular genetics …
A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16
ST Reeders, MH Breuning, KE Davies, RD Nicholls… - Nature, 1985 - nature.com
Adult polycystic kidney disease (APCKD) is a common and often lethal multi-organ disease
with an autosomal dominant pattern of inheritance; approximately 1 in 1,000 people carry …
with an autosomal dominant pattern of inheritance; approximately 1 in 1,000 people carry …
The structure and evolution of the human β-globin gene family
A Efstratiadis, JW Posakony, T Maniatis, RM Lawn… - Cell, 1980 - cell.com
We present the results of a detailed comparison of the primary structure of human β-like
globin genes and their flanking sequences. Among the sequences located 5′ to these …
globin genes and their flanking sequences. Among the sequences located 5′ to these …
Structure and evolution of the growth hormone gene family
WL Miller, NL Eberhardt - Endocrine reviews, 1983 - academic.oup.com
Introduction G ROWTH HORMONE (GH), prolactin (Prl), and chorionic somatomammotropin
(CS, placental lactogen) are a family of polypeptide hormones that are related by function …
(CS, placental lactogen) are a family of polypeptide hormones that are related by function …
The isolation of structural genes from libraries of eucaryotic DNA
T Maniatis, RC Hardison, E Lacy, J Lauer, C O'Connell… - Cell, 1978 - cell.com
We present a procedure for eucaryotic structural gene isolation which involves the
construction and screening of cloned libraries of genomic DNA. Large random DNA …
construction and screening of cloned libraries of genomic DNA. Large random DNA …
Molecular cloning and characterization of the human β-like globin gene cluster
EF Fritsch, RM Lawn, T Maniatis - Cell, 1980 - cell.com
The genes encoding human embryonic(E), fetal (Oy,“y) and adult (6, p) b-like globin
polypeptides were isolated as a set of overlapping cloned DNA fragments from …
polypeptides were isolated as a set of overlapping cloned DNA fragments from …
The Prolactin Gene Is Located on Chromosome 6 iIn Humans
D Owerbach, WJ Rutter, NE Cooke, JA Martial… - Science, 1981 - science.org
The gene for prolactin has been located on chromosome 6 in humans. DNA fragments of 4.8
and 4.0 kilobases containing prolactin gene sequences were identified in human genomic …
and 4.0 kilobases containing prolactin gene sequences were identified in human genomic …
The chromosomal arrangement of human α-like globin genes: sequence homology and α-globin gene deletions
J Lauer, CKJ Shen, T Maniatis - Cell, 1980 - cell.com
We report the isolation of a cluster of four a-like globin genes from a bacteriophage X library
of human DNA (Lawn et al., 1978). Analysis of the cloned DNA confirms the linkage …
of human DNA (Lawn et al., 1978). Analysis of the cloned DNA confirms the linkage …