Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

DQ Huang, HB El-Serag, R Loomba - Nature reviews Gastroenterology …, 2021 - nature.com
One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …

Epidemiology and risk-stratification of NAFLD-associated HCC

GN Ioannou - Journal of hepatology, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is projected to become the leading cause of
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …

From NASH to HCC: current concepts and future challenges

QM Anstee, HL Reeves, E Kotsiliti, O Govaere… - Nature reviews …, 2019 - nature.com
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …

Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2019 - Elsevier
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …

Epidemiology and management of hepatocellular carcinoma

L Kulik, HB El-Serag - Gastroenterology, 2019 - Elsevier
The major risk factors for hepatocellular carcinoma (HCC) in contemporary clinical practice
are becoming increasingly related to sustained virological response after hepatitis C …

Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update

M Omata, AL Cheng, N Kokudo, M Kudo, JM Lee… - Hepatology …, 2017 - Springer
There is great geographical variation in the distribution of hepatocellular carcinoma (HCC),
with the majority of all cases worldwide found in the Asia–Pacific region, where HCC is one …

Risk of hepatocellular cancer in patients with non-alcoholic fatty liver disease

F Kanwal, JR Kramer, S Mapakshi, Y Natarajan… - Gastroenterology, 2018 - Elsevier
Background & Aims There are limited data on the risk of hepatocellular cancer (HCC) in
patients with non-alcoholic fatty liver disease (NAFLD). We aimed to estimate the risk of …

Epidemiology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: implications for liver transplantation

ZM Younossi, G Marchesini, H Pinto-Cortez… - Transplantation, 2019 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) affects 25% of the global adult population with a
range of 13.5% in Africa and 31.8% in the Middle East. Nonalcoholic fatty liver disease is …

[HTML][HTML] Incidence of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: a systematic review, meta-analysis, and meta-regression

LA Orci, M Sanduzzi-Zamparelli, B Caballol… - Clinical …, 2022 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) may be a risk factor for
hepatocellular carcinoma (HCC), but the extent of this association still needs to be …