Cancer-associated venous thromboembolism

AA Khorana, N Mackman, A Falanga… - Nature reviews Disease …, 2022 - nature.com
Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Extracellular vesicle heterogeneity: subpopulations, isolation techniques, and diverse functions in cancer progression

E Willms, C Cabañas, I Mäger, MJA Wood… - Frontiers in …, 2018 - frontiersin.org
Cells release membrane enclosed nano-sized vesicles termed extracellular vesicles (EVs)
that function as mediators of intercellular communication by transferring biological …

[HTML][HTML] Venous thromboembolism in cancer patients: ESMO Clinical Practice Guideline

A Falanga, C Ay, M Di Nisio, G Gerotziafas… - Annals of …, 2023 - Elsevier
Thromboembolism in people with cancer still remains a major health problem and is a
leading cause of mortality after cancer itself, despite being a largely preventable disease. 1 …

Curcumin nanoparticles as promising therapeutic agents for drug targets

H Chopra, PS Dey, D Das, T Bhattacharya, M Shah… - Molecules, 2021 - mdpi.com
Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also
known across the globe for its therapeutic and medicinal benefits. The active moiety of …

Incidence of venous and arterial thromboembolic events reported in the tofacitinib rheumatoid arthritis, psoriasis and psoriatic arthritis development programmes and …

P Mease, C Charles-Schoeman, S Cohen… - Annals of the …, 2020 - ard.bmj.com
Objectives Tofacitinib is a Janus kinase inhibitor for the treatment of rheumatoid arthritis
(RA), psoriatic arthritis (PsA) and ulcerative colitis, and has been investigated in psoriasis …

Podoplanin in inflammation and cancer

M Quintanilla, L Montero-Montero, J Renart… - International journal of …, 2019 - mdpi.com
Podoplanin is a small cell-surface mucin-like glycoprotein that plays a crucial role in the
development of the alveoli, heart, and lymphatic vascular system. Emerging evidence …

Cancer therapy–associated thrombosis

SP Grover, YM Hisada, RS Kasthuri… - … , and vascular biology, 2021 - Am Heart Assoc
Patients with cancer have an increased risk of both arterial and venous thrombotic events
compared with the general population. Both the site and stage of cancer are known to …

Reactions related to CAR-T cell therapy

L Miao, Z Zhang, Z Ren, Y Li - Frontiers in immunology, 2021 - frontiersin.org
The application of chimeric antigen receptor (CAR) T-cell therapy as a tumor immunotherapy
has received great interest in recent years. This therapeutic approach has been used to treat …

Biology and role of extracellular vesicles (EVs) in the pathogenesis of thrombosis

M Zarà, GF Guidetti, M Camera, I Canobbio… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are well-established mediators of cell-to-cell communication.
EVs can be released by every cell type and they can be classified into three major groups …

Platelet-covered nanocarriers for targeted delivery of hirudin to eliminate thrombotic complication in tumor therapy

K Zhang, Z Ma, S Li, W Zhang, MF Foda, Y Zhao… - ACS …, 2022 - ACS Publications
Most patients are at high risk of thrombosis during cancer treatment. However, the major
discrepancy in the therapeutic mechanisms and microenvironment between tumors and …