An adverse foetal environment is associated with increased risk of cardiovascular,
metabolic, neuroendocrine and psychological disorders in adulthood. Exposure to stress …

Recent years have seen significant advances in our understanding of the development and
function of the adrenal gland together with further insights into the physiologic and …

An adverse early-life environment is associated with long-term disease consequences.
Adversity early in life is hypothesized to elicit developmental adaptations that serve to …

Research on the psychological development of persons with Disorders of Sex Development
(DSD) has focused on understanding the influence of atypical sex hormone exposure during …

Context Patients with classic congenital adrenal hyperplasia (CAH) are treated postnatally
with lifelong glucocorticoid (GC) replacement therapy. Previous results on general cognitive …

First-trimester prenatal treatment with the glucocorticoid (GC) dexamethasone (DEX) in
pregnancies at risk for classic congenital adrenal hyperplasia (CAH) is associated with …

Now in its twentieth year of publication, this rich collection, popular among teachers and
students alike, provides an in-depth look at major cases that have shaped the field of …

Congenital adrenal hyperplasia includes all hereditary disorders of cortisol adrenal
steroidogenesis. Seven clinical forms of congenital adrenal hyperplasia are described …

The placenta may mediate glucocorticoid-induced fetal growth restriction. Previous studies
have examined effects of fetal cortisol in sheep, which reduces placental binucleate cell …

Prenatal treatment of congenital adrenal hyperplasia (CAH) with dexamethasone (DEX) has
been in use since the mid-1980s. Its effectiveness for reducing virilization of external …