Indole clubbed 2, 4‐thiazolidinedione linked 1, 2, 3‐triazole as a potent antimalarial and antibacterial agent against drug‐resistant strain and molecular modeling …

DB Upadhyay, JA Mokariya, PJ Patel… - Archiv der …, 2024 - Wiley Online Library
In the face of escalating challenges of microbial resistance strains, this study describes the
design and synthesis of 5‐({1‐[(1H‐1, 2, 3‐triazol‐4‐yl) methyl]‐1H‐indol‐3‐yl} methylene) …

The abundant phytocannabinoids in rheumatoid arthritis: Therapeutic targets and molecular processes identified using integrated bioinformatics and network …

A Nandi, A Das, YN Dey, KK Roy - Life, 2023 - mdpi.com
The endocannabinoid system consists of several phytocannabinoids, cannabinoid
receptors, and enzymes that aid in numerous steps necessary to manifest any …

Aronia Melanocarpa Elliot anthocyanins inhibits alcoholic liver disease by activation of α7nAChR

J Wei, X Tang, Y He, Z Peng, H Liu, Y He… - Plant Foods for Human …, 2024 - Springer
The study wanted to explore the preventative effects of Aornia melanocarpa Elliot
anthocyanins (AMA) to Alcoholic liver disease (ALD) by bioinformatics prediction and …

Network pharmacology and molecular modelling study of Enhydra fluctuans for the prediction of the molecular mechanisms involved in the amelioration of …

B Chattaraj, P Khanal, A Nandi, A Das… - Journal of …, 2023 - Taylor & Francis
In view of the ethno medicinal use of Enhydra fluctuans for the treatment of kidney stones;
the present study aimed to elucidate the molecular mechanisms involved in the amelioration …

[HTML][HTML] Enhydra fluctuans Lour. aqueous extract inhibited the growth of calcium phosphate crystals: An in vitro study

B Chattaraj, A Nandi, A Das, A Baidya, S Mahata… - Food Chemistry …, 2023 - Elsevier
Enhydra fluctuans Lour. is consumed by various tribes in their ethnomedicinal practices for
the treatment of kidney stones and urinary problems. However, no scientific studies were …

Network pharmacology analysis of Plumbago zeylanica to identify the therapeutic targets and molecular mechanisms involved in ameliorating hemorrhoids

A Nandi, T Nigar, A Das, YN Dey - Journal of Biomolecular …, 2025 - Taylor & Francis
Plumbago zeylanica is an important plant used in the Ayurvedic system of medicine for the
treatment of hemorrhoids or piles. Despite its clinical uses, its molecular mechanism, for …

Protective Role of Rosmarinic Acid in Experimental Urolithiasis: Understanding Its Impact on Renal Parameters

AF Macarini, LNB Mariano, M Zanovello, RCV da Silva… - Pharmaceuticals, 2024 - mdpi.com
This study aimed to assess the ability of rosmarinic acid (RA) to prevent kidney stone
formation in an ethylene glycol and ammonium chloride (EG/AC) model. There was an …

Inhibiting brushite crystal growth: molecular docking exploration of Enhydra fluctuans phytoconstituents and their interaction with human serum albumin

A Nandi, B Chattaraj, A Das, R Prasad… - Journal of Biomolecular …, 2024 - Taylor & Francis
In our preliminary in vitro studies, the Enhydra fluctuans extract demonstrated inhibition of
calcium phosphate (brushite) crystals. Human serum albumin (HSA) is known to act as a …

[HTML][HTML] Quantum chemical calculations on calcium oxalate and dolichin A and their binding efficacy to lactoferrin: An in silico study using DFT, molecular docking …

A Acharya, M Khanal, R Maharjan, K Gyawali… - AIMS …, 2024 - aimspress.com
Lactoferrin, a member of the transferrin family, is one of the promoter proteins for calcium
oxalate-type kidney stone formation. It exhibits a remarkable ability to interact with metals …

Factors prevailing for gallstone formation

GPK Bali, B Singh, M Ashraf… - … , Diagnosis, Treatment and …, 2024 - Elsevier
Cholelithiasis is the presence of gallstones, which are concretions that form in the biliary
tract, usually in the gallbladder. Gallstones are hardened deposits of the digestive fluid “bile” …