The insula: a brain stimulation target for the treatment of addiction

C Ibrahim, DS Rubin-Kahana, A Pushparaj… - Frontiers in …, 2019 - frontiersin.org
Substance use disorders (SUDs) are a growing public health concern with only a limited
number of approved treatments. However, even approved treatments are subject to limited …

The hypodopaminergic state ten years after: transcranial magnetic stimulation as a tool to test the dopamine hypothesis of drug addiction

A Sanna, L Fattore, P Badas, G Corona… - Current Opinion in …, 2021 - Elsevier
An altered dopamine transmission has been described for different types of addiction for a
long time. Preclinical and clinical evidence support the hypodopaminergic hypothesis and …

Continuous high frequency deep brain stimulation of the rat anterior insula attenuates the relapse post withdrawal and strengthens the extinction of morphine seeking

H Chang, C Gao, K Sun, L Xiao, X Li, S Jiang… - Frontiers in …, 2020 - frontiersin.org
Deep brain stimulation (DBS) modulates the neuronal activity in specific brain circuits and
has been recently considered as a promising intervention for refractory addiction. The insula …

Repeated blast model of mild traumatic brain injury alters oxycodone self‐administration and drug seeking

NN Nawarawong, M Slaker, M Muelbl… - European journal of …, 2019 - Wiley Online Library
Each year, traumatic brain injuries (TBI) affect millions worldwide. Mild TBI s (mTBI) are the
most prevalent and can lead to a range of neurobehavioral problems, including substance …

Decreased excitability of leptin-sensitive anterior insula pyramidal neurons in a rat model of compulsive food demand

D Kirson, SRS Bagsic, J Murphy, H Chang… - …, 2022 - Elsevier
Compulsive eating is an overlapping construct with binge eating that shares many
characteristics with substance use disorders. Compulsive eating may impact millions of …

[HTML][HTML] Role of deep brain stimulation (DBS) in addiction disorders

J Iqbal, MNM Mansour, HA Saboor… - Surgical Neurology …, 2023 - ncbi.nlm.nih.gov
Background: Addiction disorders pose significant challenges to public health, necessitating
innovative treatments. This assesses deep brain stimulation (DBS) as a potential …

Sex differences in the long-term consequences of stroke

CE Stewart, TE Branyan, D Sampath… - Sex Differences in Brain …, 2022 - Springer
Stroke is the fifth leading cause of death and as healthcare intervention improves, the
number of stroke survivors has also increased. Furthermore, there exists a subgroup of …

On the Role of Insula in Drug Addiction

R Shah - Science Insights, 2023 - bonoi.org
Drug addiction is a chronic, relapsing brain disease with limited treatment options and a
high recurrence rate. Neuromodulation techniques, including repetitive transcranial …

脑岛在成瘾中的结构和功能异常

贺馨宇, 何清华 - 心理科学进展, 2021 - journal.psych.ac.cn
脑岛位于大脑外侧裂的深处, 与情绪和内感受等多种心理功能有关. 脑岛在成瘾中的结构变化和
功能连接异常, 表明了脑岛在成瘾中的作用, 刺激脑岛区域干预成瘾也逐渐成为研究者们关注的 …

Characterisation of the role of peripheral μ-opioid receptors in the behavioural effects of heroin and their underlying neural systems in the rat

D Joshi - 2024 - repository.cam.ac.uk
The behavioural effects of opioids such as heroin have long been considered to be
mediated by central mechanisms. However in recreational use, opioids are administered …