Manipulating enzymes properties with DNA nanostructures

A Jaekel, P Stegemann, B Saccà - Molecules, 2019 - mdpi.com
Nucleic acids and proteins are two major classes of biopolymers in living systems. Whereas
nucleic acids are characterized by robust molecular recognition properties, essential for the …

DNA origami as emerging technology for the engineering of fluorescent and plasmonic-based biosensors

M Loretan, I Domljanovic, M Lakatos, C Rüegg… - Materials, 2020 - mdpi.com
DNA nanotechnology is a powerful and promising tool for the development of nanoscale
devices for numerous and diverse applications. One of the greatest potential fields of …

Arranging small molecules with subnanometer precision on DNA origami substrates for the single‐molecule investigation of protein–ligand interactions

J Huang, A Suma, M Cui, G Grundmeier… - Small …, 2020 - Wiley Online Library
DNA origami nanostructures are versatile substrates for the single‐molecule investigation of
biomolecular interactions as they enable the display of molecular species in complex …

[HTML][HTML] A molecular device: A DNA molecular lock driven by the nicking enzymes

X Zhang, Q Zhang, Y Liu, B Wang, S Zhou - Computational and Structural …, 2020 - Elsevier
As people are placing more and more importance on information security, how to realize the
protection of information has become a hotspot of current research. As a security device …

Magnesium-free immobilization of DNA origami nanostructures at mica surfaces for atomic force microscopy

Y Xin, AA Zargariantabrizi, G Grundmeier, A Keller - Molecules, 2021 - mdpi.com
DNA origami nanostructures (DONs) are promising substrates for the single-molecule
investigation of biomolecular reactions and dynamics by in situ atomic force microscopy …

Sequence-selective purification of biological RNAs using DNA nanoswitches

L Zhou, A Hayden, AR Chandrasekaran… - Cell reports …, 2021 - cell.com
Nucleic acid purification is a critical aspect of biomedical research and a multibillion-dollar
industry. Here we establish sequence-selective RNA capture, release, and isolation using …

[HTML][HTML] Piggybacking functionalized DNA nanostructures into live cell nuclei

GM Roozbahani, P Colosi, A Oravecz, EM Sorokina… - bioRxiv, 2024 - ncbi.nlm.nih.gov
DNA origami (DO) are promising tools for in vitro or in vivo applications including drug
delivery; biosensing, detecting biomolecules; and probing chromatin sub-structures …