Losing Genes: The Evolutionary Remodeling of Cetacea Skin

G Espregueira Themudo, LQ Alves… - Frontiers in Marine …, 2020 - frontiersin.org
The skin is a multi-layered organ, often displaying associated structures, that establishes a
protective interface between the organism and the surrounding environment. In mammals …

Gene duplications and gene loss in the epidermal differentiation complex during the evolutionary land-to-water transition of cetaceans

KB Holthaus, J Lachner, B Ebner, E Tschachler… - Scientific Reports, 2021 - nature.com
Major protein components of the mammalian skin barrier are encoded by genes clustered in
the Epidermal Differentiation Complex (EDC). The skin of cetaceans, ie whales, porpoises …

PseudoChecker: an integrated online platform for gene inactivation inference

LQ Alves, R Ruivo, MM Fonseca… - Nucleic Acids …, 2020 - academic.oup.com
The rapid expansion of high-quality genome assemblies, exemplified by ongoing initiatives
such as the Genome-10K and i5k, demands novel automated methods to approach …

Functional or vestigial? The genomics of the pineal gland in Xenarthra

R Valente, F Alves, I Sousa-Pinto, R Ruivo… - Journal of Molecular …, 2021 - Springer
Vestigial organs are historical echoes of past phenotypes. Determining whether a specific
organ constitutes a functional or vestigial structure can be a challenging task, given that …

[HTML][HTML] Convergent Cortistatin losses parallel modifications in circadian rhythmicity and energy homeostasis in Cetacea and other mammalian lineages

R Valente, LQ Alves, M Nabais, F Alves, I Sousa-Pinto… - Genomics, 2021 - Elsevier
The ancestors of Cetacea underwent profound morpho-physiological alterations. By
displaying an exclusive aquatic existence, cetaceans evolved unique patterns of locomotor …

Уровень хемокинов, продуцируемых кератиноцитами и фибробластами кожи, при абдоминопластике у пациентов с нормальной массой тела и ожирением

АЕ Копасов, ЕН Волкова, СН Блохин… - Патологическая …, 2020 - pfiet.ru
Аннотация Цель работы–определение уровня хемокинов, ассоциированных с
фибробластами и кератиноцитами, в клетках кожи, выделеных из операционного …

When less is more: the untold stories in Cetacea genomes

BGS Felipe - 2023 - repositorio.ul.pt
Cetacea are one of the very few mammalian lineages to be composed of uniquely aquatic
species, commonly known as whales, dolphins and porpoises. As the first cetacean …

Expression Analysis of CCL27: A Sensitive biomarker in distinguishing between psoriasis and atopic dermatitis

AM Elrefaei, MO Elhamshary, HA Ismail… - Research Journal of …, 2022 - journals.ekb.eg
Background and objective: Eczema and psoriasis are heterogeneous cutaneous
inflammatory disorders with broad and occasionally overlapping diagnostic criteria, making …

[PDF][PDF] NRfinder: A pipeline for the characterization of the number and type of nuclear receptors in a genomic sequence

MAP Domingues - 2021 - repositorio-aberto.up.pt
The nuclear receptor superfamily consists of a highly diverse group of transcription factors
exclusive to metazoans. These receptors perform a central role in the regulation of most …

Differential Cetacea Circadian Rhythmicity is associated with the molecular erosion of Cortistatin

R Valente, LQ Alves, M Nabais, F Alves, I Sousa-Pinto… - bioRxiv, 2020 - biorxiv.org
The ancestors of Cetacea underwent profound morpho-physiological alterations. By
displaying an exclusive aquatic existence, cetaceans evolved unique patterns of locomotor …