Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

Our understanding of protective versus pathological immune responses to SARS-CoV-2, the
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …

While preventing vertical HIV transmission has been very successful, HIV-exposed
uninfected infants (iHEU) experience an elevated risk to infections compared to HIV …

The latent HIV-1 reservoir represents a major barrier to achieving a long-term antiretroviral
therapy (ART)-free remission or cure for HIV-1. Natural Killer (NK) cells are innate immune …

We developed a comprehensive method for functional assessment of the changes in
immune populations and killing activity of peripheral blood mononuclear cells after …

Timely initiation of antiretroviral therapy (ART) remains a major challenge in the effort to treat
children living with HIV (“CLH”) and little is known regarding the dynamics of immune …

To investigate the effects of allo-Treg cells, allo-NK cells, and their mixtures in different
proportions on Graft-versus-host disease (GVHD) in bone marrow transplant mouse model …

While preventing vertical HIV transmission has been very successful, the increasing number
of HIV-exposed uninfected infants (iHEU) experience an elevated risk to infections …

We present here a comprehensive body of novel research that deeply interrogates the NK
cell response in the setting of SARS-CoV-2 infection. Due to their intrinsic ability to lyse …

Natural killer (NK) cells are innate immune cells with a crucial role in the early anti-viral and
anti-cancer immune responses. In this thesis, I present two distinct projects in which the …