Mechanistic landscape of membrane-permeabilizing peptides
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …
The role of bacterial lipid diversity and membrane properties in modulating antimicrobial peptide activity and drug resistance
This review provides an analysis of the role that membrane composition and structure plays
in the resistance of microorganisms to antimicrobial peptides (AMPs). We describe the …
in the resistance of microorganisms to antimicrobial peptides (AMPs). We describe the …
Hydrophilic nanoparticles that kill bacteria while sparing mammalian cells reveal the antibiotic role of nanostructures
To dissect the antibiotic role of nanostructures from chemical moieties belligerent to both
bacterial and mammalian cells, here we show the antimicrobial activity and cytotoxicity of …
bacterial and mammalian cells, here we show the antimicrobial activity and cytotoxicity of …
[HTML][HTML] Atomic force microscopy to elucidate how peptides disrupt membranes
K Hammond, MG Ryadnov… - Biochimica et Biophysica …, 2021 - Elsevier
Atomic force microscopy is an increasingly attractive tool to study how peptides disrupt
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …
Allosteric modulation of ghrelin receptor signaling by lipids
M Damian, M Louet, AAS Gomes, C M'kadmi… - Nature …, 2021 - nature.com
The membrane is an integral component of the G protein-coupled receptor signaling
machinery. Here we demonstrate that lipids regulate the signaling efficacy and selectivity of …
machinery. Here we demonstrate that lipids regulate the signaling efficacy and selectivity of …
Exploring molecular-biomembrane interactions with surface plasmon resonance and dual polarization interferometry technology: expanding the spotlight onto …
TH Lee, DJ Hirst, K Kulkarni, MP Del Borgo… - Chemical …, 2018 - ACS Publications
The molecular analysis of biomolecular-membrane interactions is central to understanding
most cellular systems but has emerged as a complex technical challenge given the …
most cellular systems but has emerged as a complex technical challenge given the …
Nanoscale structural response of biomimetic cell membranes to controlled dehydration
Although cell membranes exist in excess of water under physiological conditions, there are
a number of biochemical processes, such as adsorption of biomacromolecules or …
a number of biochemical processes, such as adsorption of biomacromolecules or …
The intricate link between membrane lipid structure and composition and membrane structural properties in bacterial membranes
It is now evident that the cell manipulates lipid composition to regulate different processes
such as membrane protein insertion, assembly and function. Moreover, changes in …
such as membrane protein insertion, assembly and function. Moreover, changes in …
The effect of membrane thickness on the membrane permeabilizing activity of the cyclic lipopeptide tolaasin II
J Steigenberger, C Mergen, V De Roo… - Frontiers in Molecular …, 2022 - frontiersin.org
Tolaasin II is an amphiphilic, membrane-active, cyclic lipopeptide produced by
Pseudomonas tolaasii and is responsible for brown blotch disease in mushroom. To better …
Pseudomonas tolaasii and is responsible for brown blotch disease in mushroom. To better …
[HTML][HTML] The antimicrobial peptide maculatin self assembles in parallel to form a pore in phospholipid bilayers
Little is known experimentally about the detailed orientation of membrane-bound maculatin
1.1 (Mac1), an antimicrobial peptide from the skin secretions of Australian tree frogs. In this …
1.1 (Mac1), an antimicrobial peptide from the skin secretions of Australian tree frogs. In this …