Linear growth during three distinct stages of life determines attained stature in adulthood:
namely, in utero, early postnatal life, and puberty and the adolescent period. Individual host …

A major question in developmental and regenerative biology is how organ size and
architecture are controlled by progenitor cells. While limb bones exhibit catch-up growth …

Endochondral ossification requires proper control of chondrocyte proliferation,
differentiation, survival, and organization. Here we show that knockout of α-parvin, an …

Background: Undernutrition impairs linear growth while restoration of nutritional provisions
leads to accelerated growth patterns. However, the composition of the nutrition provided is …

Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by the deficiency
of the survival motor neuron (SMN) protein, which leads to motor neuron dysfunction and …

The resting zone (RZ) in mammalian growth plates is critical for maintaining and regulating
chondrocyte turnover during longitudinal bone growth as a control tower and stem cell …

A major question in developmental and regenerative biology is how organ size is controlled
by progenitor cells. For example, while limb bones exhibit catch-up growth (recovery of a …

Most of our bone are formed thought a process called endochondral ossification, which is a
tiny, regulated process leaded by the chondrocytes of the GP and which require continuous …